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The ageing systemic milieu negatively regulates neurogenesis and cognitive function.
Villeda SA, Luo J, Mosher KI, Zou B, Britschgi M, Bieri G, Stan TM, Fainberg N, Ding Z, Eggel A, Lucin KM, Czirr E, Park JS, Couillard-Després S, Aigner L, Li G, Peskind ER, Kaye JA, Quinn JF, Galasko DR, Xie XS, Rando TA, Wyss-Coray T. Villeda SA, et al. Among authors: aigner l. Nature. 2011 Aug 31;477(7362):90-4. doi: 10.1038/nature10357. Nature. 2011. PMID: 21886162 Free PMC article.
Clonally expanded CD8 T cells patrol the cerebrospinal fluid in Alzheimer's disease.
Gate D, Saligrama N, Leventhal O, Yang AC, Unger MS, Middeldorp J, Chen K, Lehallier B, Channappa D, De Los Santos MB, McBride A, Pluvinage J, Elahi F, Tam GK, Kim Y, Greicius M, Wagner AD, Aigner L, Galasko DR, Davis MM, Wyss-Coray T. Gate D, et al. Among authors: aigner l. Nature. 2020 Jan;577(7790):399-404. doi: 10.1038/s41586-019-1895-7. Epub 2020 Jan 8. Nature. 2020. PMID: 31915375 Free PMC article.
Structural and functional rejuvenation of the aged brain by an approved anti-asthmatic drug.
Marschallinger J, Schäffner I, Klein B, Gelfert R, Rivera FJ, Illes S, Grassner L, Janssen M, Rotheneichner P, Schmuckermair C, Coras R, Boccazzi M, Chishty M, Lagler FB, Renic M, Bauer HC, Singewald N, Blümcke I, Bogdahn U, Couillard-Despres S, Lie DC, Abbracchio MP, Aigner L. Marschallinger J, et al. Among authors: aigner l. Nat Commun. 2015 Oct 27;6:8466. doi: 10.1038/ncomms9466. Nat Commun. 2015. PMID: 26506265 Free PMC article.
In vivo imaging of adult neurogenesis.
Couillard-Despres S, Aigner L. Couillard-Despres S, et al. Among authors: aigner l. Eur J Neurosci. 2011 Mar;33(6):1037-44. doi: 10.1111/j.1460-9568.2011.07601.x. Eur J Neurosci. 2011. PMID: 21395846 Review.
Transient expression of doublecortin during adult neurogenesis.
Brown JP, Couillard-Després S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG. Brown JP, et al. Among authors: aigner l. J Comp Neurol. 2003 Dec 1;467(1):1-10. doi: 10.1002/cne.10874. J Comp Neurol. 2003. PMID: 14574675
Neurogenesis and neuronal regeneration in status epilepticus.
Rotheneichner P, Marschallinger J, Couillard-Despres S, Aigner L. Rotheneichner P, et al. Among authors: aigner l. Epilepsia. 2013 Sep;54 Suppl 6:40-2. doi: 10.1111/epi.12274. Epilepsia. 2013. PMID: 24001070 Free article. Review.
CD4+ T cells contribute to neurodegeneration in Lewy body dementia.
Gate D, Tapp E, Leventhal O, Shahid M, Nonninger TJ, Yang AC, Strempfl K, Unger MS, Fehlmann T, Oh H, Channappa D, Henderson VW, Keller A, Aigner L, Galasko DR, Davis MM, Poston KL, Wyss-Coray T. Gate D, et al. Among authors: aigner l. Science. 2021 Nov 12;374(6569):868-874. doi: 10.1126/science.abf7266. Epub 2021 Oct 14. Science. 2021. PMID: 34648304 Free PMC article.
Ageing abolishes the effects of fluoxetine on neurogenesis.
Couillard-Despres S, Wuertinger C, Kandasamy M, Caioni M, Stadler K, Aigner R, Bogdahn U, Aigner L. Couillard-Despres S, et al. Among authors: aigner l, aigner r. Mol Psychiatry. 2009 Sep;14(9):856-64. doi: 10.1038/mp.2008.147. Epub 2009 Jan 13. Mol Psychiatry. 2009. PMID: 19139747
Transforming growth factor-beta1 is a negative modulator of adult neurogenesis.
Wachs FP, Winner B, Couillard-Despres S, Schiller T, Aigner R, Winkler J, Bogdahn U, Aigner L. Wachs FP, et al. Among authors: aigner l, aigner r. J Neuropathol Exp Neurol. 2006 Apr;65(4):358-70. doi: 10.1097/01.jnen.0000218444.53405.f0. J Neuropathol Exp Neurol. 2006. PMID: 16691117
204 results