Ahn S - Search Results

1

Design and characterization of cereblon-mediated androgen receptor proteolysis-targeting chimeras.

Takwale AD, Jo SH, Jeon YU, Kim HS, Shin CH, Lee HK, Ahn S, Lee CO, Du Ha J, Kim JH, Hwang JY. Takwale AD, et al. Among authors: ahn s. Eur J Med Chem. 2020 Dec 15;208:112769. doi: 10.1016/j.ejmech.2020.112769. Epub 2020 Aug 26. Eur J Med Chem. 2020. PMID: 32961381

2

Novel 2,4-diaminopyrimidines bearing tetrahydronaphthalenyl moiety against anaplastic lymphoma kinase (ALK): Synthesis, in vitro, ex vivo, and in vivo efficacy studies.

Song D, Lee M, Park CH, Ahn S, Yun CS, Lee CO, Kim HR, Hwang JY. Song D, et al. Among authors: ahn s. Bioorg Med Chem Lett. 2016 Apr 1;26(7):1720-5. doi: 10.1016/j.bmcl.2016.02.052. Epub 2016 Feb 20. Bioorg Med Chem Lett. 2016. PMID: 26923695

3

Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera.

Kim K, Lee DH, Park S, Jo SH, Ku B, Park SG, Park BC, Jeon YU, Ahn S, Kang CH, Hwang D, Chae S, Ha JD, Kim S, Hwang JY, Kim JH. Kim K, et al. Among authors: ahn s. Sci Rep. 2019 Dec 23;9(1):19654. doi: 10.1038/s41598-019-56177-5. Sci Rep. 2019. PMID: 31873151 Free PMC article.

4

Synthesis and evaluation of novel 2,4-diaminopyrimidines bearing bicyclic aminobenzazepines for anaplastic lymphoma kinase (ALK) inhibitor.

Kang GA, Lee M, Song D, Lee HK, Ahn S, Park CH, Lee CO, Yun CS, Jung H, Kim P, Ha JD, Cho SY, Kim HR, Hwang JY. Kang GA, et al. Among authors: ahn s. Bioorg Med Chem Lett. 2015 Sep 15;25(18):3992-8. doi: 10.1016/j.bmcl.2015.07.004. Epub 2015 Jul 17. Bioorg Med Chem Lett. 2015. PMID: 26235945

5

Discovery of novel tetrahydroisoquinoline-containing pyrimidines as ALK inhibitors.

Achary R, Yun JI, Park CM, Mathi GR, Lee JY, Ha JD, Chae CH, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Achary R, et al. Among authors: ahn s. Bioorg Med Chem. 2016 Jan 15;24(2):207-19. doi: 10.1016/j.bmc.2015.12.004. Epub 2015 Dec 7. Bioorg Med Chem. 2016. PMID: 26712094

6

Minor modifications to ceritinib enhance anti-tumor activity in EML4-ALK positive cancer.

Kang CH, Kim EY, Kim HR, Lee CO, Lee HK, Jeong HG, Choi SU, Yun CS, Hwang JY, Lee JY, Son YH, Ahn S, Lee BH, Jung H, Park CH. Kang CH, et al. Among authors: ahn s. Cancer Lett. 2016 May 1;374(2):272-8. doi: 10.1016/j.canlet.2016.02.009. Epub 2016 Feb 26. Cancer Lett. 2016. PMID: 26923554

7

Replacing the terminal piperidine in ceritinib with aliphatic amines confers activities against crizotinib-resistant mutants including G1202R.

Mathi GR, Kang CH, Lee HK, Achary R, Lee HY, Lee JY, Ha JD, Ahn S, Park CH, Lee CO, Hwang JY, Yun CS, Jung HJ, Cho SY, Kim HR, Kim P. Mathi GR, et al. Among authors: ahn s. Eur J Med Chem. 2017 Jan 27;126:536-549. doi: 10.1016/j.ejmech.2016.11.046. Epub 2016 Nov 24. Eur J Med Chem. 2017. PMID: 27915169

8

Synthesis and Molecular Modeling Studies of N'-Hydroxyindazolecarboximidamides as Novel Indoleamine 2,3-Dioxygenase 1 (IDO1) Inhibitors.

Lee DH, Lee JY, Jeong J, Kim M, Lee KW, Jang E, Ahn S, Lee CH, Hwang JY. Lee DH, et al. Among authors: ahn s. Molecules. 2017 Nov 9;22(11):1936. doi: 10.3390/molecules22111936. Molecules. 2017. PMID: 29120388 Free PMC article.

9

Discovery of a Novel Chemical Scaffold Against Mutant Isocitrate Dehydrogenase 1 (IDH1).

Kang CH, Choi SU, Son YH, Lee HK, Jeong HG, Yun CS, Ahn S, Park CH. Kang CH, et al. Among authors: ahn s. Anticancer Res. 2020 Sep;40(9):4929-4935. doi: 10.21873/anticanres.14496. Anticancer Res. 2020. PMID: 32878781

10

Discovery of novel 2-aryl-4-benzoyl-imidazole (ABI-III) analogues targeting tubulin polymerization as antiproliferative agents.

Chen J, Ahn S, Wang J, Lu Y, Dalton JT, Miller DD, Li W. Chen J, et al. Among authors: ahn s. J Med Chem. 2012 Aug 23;55(16):7285-9. doi: 10.1021/jm300564b. Epub 2012 Aug 6. J Med Chem. 2012. PMID: 22783954 Free PMC article.

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