Ahmed YA - Search Results

1

Evidence of a putative glycosaminoglycan binding site on the glycosylated SARS-CoV-2 spike protein N-terminal domain.

Schuurs ZP, Hammond E, Elli S, Rudd TR, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Bagdonaite I, Yang Z, Ahmed YA, Richard DJ, Turnbull J, Ferro V, Coombe DR, Gandhi NS. Schuurs ZP, et al. Among authors: ahmed ya. Comput Struct Biotechnol J. 2021;19:2806-2818. doi: 10.1016/j.csbj.2021.05.002. Epub 2021 May 4. Comput Struct Biotechnol J. 2021. PMID: 33968333 Free PMC article.

2

Diversification of the structural determinants of fibroblast growth factor-heparin interactions: implications for binding specificity.

Xu R, Ori A, Rudd TR, Uniewicz KA, Ahmed YA, Guimond SE, Skidmore MA, Siligardi G, Yates EA, Fernig DG. Xu R, et al. Among authors: ahmed ya. J Biol Chem. 2012 Nov 16;287(47):40061-73. doi: 10.1074/jbc.M112.398826. Epub 2012 Sep 27. J Biol Chem. 2012. PMID: 23019343 Free PMC article.

3

Generating heparan sulfate saccharide libraries for glycomics applications.

Powell AK, Ahmed YA, Yates EA, Turnbull JE. Powell AK, et al. Among authors: ahmed ya. Nat Protoc. 2010 May;5(5):821-33. doi: 10.1038/nprot.2010.17. Epub 2010 Apr 8. Nat Protoc. 2010. PMID: 20379137

4

Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity.

Ahmed YA, Yates EA, Moss DJ, Loeven MA, Hussain SA, Hohenester E, Turnbull JE, Powell AK. Ahmed YA, et al. Mol Biosyst. 2016 Oct 20;12(10):3166-75. doi: 10.1039/c6mb00432f. Epub 2016 Aug 9. Mol Biosyst. 2016. PMID: 27502551 Free PMC article.

5

Glycomics profiling of heparan sulfate structure and activity.

Turnbull JE, Miller RL, Ahmed Y, Puvirajesinghe TM, Guimond SE. Turnbull JE, et al. Methods Enzymol. 2010;480:65-85. doi: 10.1016/S0076-6879(10)80004-7. Methods Enzymol. 2010. PMID: 20816205 Review.

6

Array-based functional screening of heparin glycans.

Puvirajesinghe TM, Ahmed YA, Powell AK, Fernig DG, Guimond SE, Turnbull JE. Puvirajesinghe TM, et al. Among authors: ahmed ya. Chem Biol. 2012 May 25;19(5):553-8. doi: 10.1016/j.chembiol.2012.03.011. Chem Biol. 2012. PMID: 22633407

7

A molecular mechanism for the heparan sulfate dependence of slit-robo signaling.

Hussain SA, Piper M, Fukuhara N, Strochlic L, Cho G, Howitt JA, Ahmed Y, Powell AK, Turnbull JE, Holt CE, Hohenester E. Hussain SA, et al. J Biol Chem. 2006 Dec 22;281(51):39693-8. doi: 10.1074/jbc.M609384200. Epub 2006 Oct 24. J Biol Chem. 2006. PMID: 17062560 Free PMC article.

8

Dendrimer Heparan Sulfate Glycomimetics: Potent Heparanase Inhibitors for Anticancer Therapy.

Zubkova OV, Ahmed YA, Guimond SE, Noble SL, Miller JH, Alfred Smith RA, Nurcombe V, Tyler PC, Weissmann M, Vlodavsky I, Turnbull JE. Zubkova OV, et al. Among authors: ahmed ya. ACS Chem Biol. 2018 Dec 21;13(12):3236-3242. doi: 10.1021/acschembio.8b00909. Epub 2018 Nov 29. ACS Chem Biol. 2018. PMID: 30480427

9

Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry.

Tissot B, Gasiunas N, Powell AK, Ahmed Y, Zhi ZL, Haslam SM, Morris HR, Turnbull JE, Gallagher JT, Dell A. Tissot B, et al. Glycobiology. 2007 Sep;17(9):972-82. doi: 10.1093/glycob/cwm072. Epub 2007 Jul 10. Glycobiology. 2007. PMID: 17623722

10

Differential scanning fluorimetry measurement of protein stability changes upon binding to glycosaminoglycans: a screening test for binding specificity.

Uniewicz KA, Ori A, Xu R, Ahmed Y, Wilkinson MC, Fernig DG, Yates EA. Uniewicz KA, et al. Anal Chem. 2010 May 1;82(9):3796-802. doi: 10.1021/ac100188x. Anal Chem. 2010. PMID: 20353159

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