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Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
Ahuno ST, Doebley AL, Ahearn TU, Yarney J, Titiloye N, Hamel N, Adjei E, Clegg-Lamptey JN, Edusei L, Awuah B, Song X, Vanderpuye V, Abubakar M, Duggan M, Stover DG, Nyarko K, Bartlett JMS, Aitpillah F, Ansong D, Gardner KL, Boateng FA, Bowcock AM, Caldas C, Foulkes WD, Wiafe S, Wiafe-Addai B, Garcia-Closas M, Kwarteng A, Ha G, Figueroa JD, Polak P; Ghana Breast Health Study Team. Ahuno ST, et al. NPJ Precis Oncol. 2021 Sep 17;5(1):83. doi: 10.1038/s41698-021-00219-7. NPJ Precis Oncol. 2021. PMID: 34535742 Free PMC article.
Discovery of structural deletions in breast cancer predisposition genes using whole genome sequencing data from > 2000 women of African-ancestry.
Chen Z, Guo X, Long J, Ping J, Li B, Fadden MK, Ahearn TU, Stram DO, Shu XO, Jia G, Figueroa J; Ghana Breast Health Study team; Palmer JR, Sanderson M, Haiman CA, Blot WJ, Garcia-Closas M, Cai Q, Zheng W. Chen Z, et al. Hum Genet. 2021 Oct;140(10):1449-1457. doi: 10.1007/s00439-021-02342-8. Epub 2021 Aug 27. Hum Genet. 2021. PMID: 34487234 Free PMC article.