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Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.
Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. Wang Z, et al. Among authors: aguilar eg. Nat Med. 2019 Jan;25(1):141-151. doi: 10.1038/s41591-018-0221-5. Epub 2018 Nov 12. Nat Med. 2019. PMID: 30420753 Free PMC article.
Models to Study NK Cell Biology and Possible Clinical Application.
Zamora AE, Grossenbacher SK, Aguilar EG, Murphy WJ. Zamora AE, et al. Among authors: aguilar eg. Curr Protoc Immunol. 2015 Aug 3;110:14.37.1-14.37.14. doi: 10.1002/0471142735.im1437s110. Curr Protoc Immunol. 2015. PMID: 26237009 Free PMC article. Review.
Targeted Rho-associated kinase 2 inhibition suppresses murine and human chronic GVHD through a Stat3-dependent mechanism.
Flynn R, Paz K, Du J, Reichenbach DK, Taylor PA, Panoskaltsis-Mortari A, Vulic A, Luznik L, MacDonald KK, Hill GR, Nyuydzefe MS, Weiss JM, Chen W, Trzeciak A, Serody JS, Aguilar EG, Murphy WJ, Maillard I, Munn D, Koreth J, Cutler CS, Antin JH, Ritz J, Waksal SD, Zanin-Zhorov A, Blazar BR. Flynn R, et al. Among authors: aguilar eg. Blood. 2016 Apr 28;127(17):2144-54. doi: 10.1182/blood-2015-10-678706. Epub 2016 Mar 16. Blood. 2016. PMID: 26983850 Free PMC article.
Leveraging natural killer cells for cancer immunotherapy.
Grossenbacher SK, Aguilar EG, Murphy WJ. Grossenbacher SK, et al. Among authors: aguilar eg. Immunotherapy. 2017 May;9(6):487-497. doi: 10.2217/imt-2017-0013. Immunotherapy. 2017. PMID: 28472904 Free PMC article. Review.
Licensing delineates helper and effector NK cell subsets during viral infection.
Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ. Zamora AE, et al. Among authors: aguilar eg. JCI Insight. 2017 May 18;2(10):e87032. doi: 10.1172/jci.insight.87032. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515356 Free PMC article.
Minimal PD-1 expression in mouse and human NK cells under diverse conditions.
Judge SJ, Dunai C, Aguilar EG, Vick SC, Sturgill IR, Khuat LT, Stoffel KM, Van Dyke J, Longo DL, Darrow MA, Anderson SK, Blazar BR, Monjazeb AM, Serody JS, Canter RJ, Murphy WJ. Judge SJ, et al. Among authors: aguilar eg. J Clin Invest. 2020 Jun 1;130(6):3051-3068. doi: 10.1172/JCI133353. J Clin Invest. 2020. PMID: 32134744 Free PMC article.
Repurposing a novel anti-cancer RXR agonist to attenuate murine acute GVHD and maintain graft-versus-leukemia responses.
Thangavelu G, Wang C, Loschi M, Saha A, Osborn MJ, Furlan SN, Aoyama K, McDonald-Hyman C, Aguilar EG, Janesick AS, Chandraratna RA, Refaeli Y, Panoskaltsis-Mortari A, MacDonald KP, Hill GR, Zeiser R, Maillard I, Serody JS, Murphy WJ, Munn DH, Blumberg B, Brown C, Kuchroo V, Kean LS, Hippen KL, Noelle RJ, Blazar BR. Thangavelu G, et al. Among authors: aguilar eg. Blood. 2021 Feb 25;137(8):1090-1103. doi: 10.1182/blood.2020005628. Blood. 2021. PMID: 32976550 Free PMC article.
34 results