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TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.
Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J. Davizon-Castillo P, et al. Among authors: aguila s. Blood. 2019 Aug 29;134(9):727-740. doi: 10.1182/blood.2019000200. Epub 2019 Jul 16. Blood. 2019. PMID: 31311815 Free PMC article.
Novel insights into the clinical phenotype and pathophysiology underlying low VWF levels.
Lavin M, Aguila S, Schneppenheim S, Dalton N, Jones KL, O'Sullivan JM, O'Connell NM, Ryan K, White B, Byrne M, Rafferty M, Doyle MM, Nolan M, Preston RJS, Budde U, James P, Di Paola J, O'Donnell JS. Lavin M, et al. Among authors: aguila s. Blood. 2017 Nov 23;130(21):2344-2353. doi: 10.1182/blood-2017-05-786699. Epub 2017 Sep 15. Blood. 2017. PMID: 28916584 Free PMC article. Clinical Trial.
Significant gynecological bleeding in women with low von Willebrand factor levels.
Lavin M, Aguila S, Dalton N, Nolan M, Byrne M, Ryan K, White B, O'Connell NM, O'Sullivan JM, Di Paola J, James PD, O'Donnell JS. Lavin M, et al. Among authors: aguila s. Blood Adv. 2018 Jul 24;2(14):1784-1791. doi: 10.1182/bloodadvances.2018017418. Blood Adv. 2018. PMID: 30042144 Free PMC article. Clinical Trial.
Amelioration of the severity of heparin-binding antithrombin mutations by posttranslational mosaicism.
Martínez-Martínez I, Navarro-Fernández J, Østergaard A, Gutiérrez-Gallego R, Padilla J, Bohdan N, Miñano A, Pascual C, Martínez C, de la Morena-Barrio ME, Aguila S, Pedersen S, Kristensen SR, Vicente V, Corral J. Martínez-Martínez I, et al. Among authors: aguila s. Blood. 2012 Jul 26;120(4):900-4. doi: 10.1182/blood-2012-01-406207. Epub 2012 Apr 12. Blood. 2012. PMID: 22498748 Free article.
von Willebrand factor links primary hemostasis to innate immunity.
Drakeford C, Aguila S, Roche F, Hokamp K, Fazavana J, Cervantes MP, Curtis AM, Hawerkamp HC, Dhami SPS, Charles-Messance H, Hackett EE, Chion A, Ward S, Ahmad A, Schoen I, Breen E, Keane J, Murphy R, Preston RJS, O'Sullivan JM, Sheedy FJ, Fallon P, O'Donnell JS. Drakeford C, et al. Among authors: aguila s. Nat Commun. 2022 Nov 3;13(1):6320. doi: 10.1038/s41467-022-33796-7. Nat Commun. 2022. PMID: 36329021 Free PMC article.
68 results