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SMARCA4 loss is synthetic lethal with CDK4/6 inhibition in non-small cell lung cancer.
Xue Y, Meehan B, Fu Z, Wang XQD, Fiset PO, Rieker R, Levins C, Kong T, Zhu X, Morin G, Skerritt L, Herpel E, Venneti S, Martinez D, Judkins AR, Jung S, Camilleri-Broet S, Gonzalez AV, Guiot MC, Lockwood WW, Spicer JD, Agaimy A, Pastor WA, Dostie J, Rak J, Foulkes WD, Huang S. Xue Y, et al. Among authors: agaimy a. Nat Commun. 2019 Feb 4;10(1):557. doi: 10.1038/s41467-019-08380-1. Nat Commun. 2019. PMID: 30718506 Free PMC article.
ISL1 expression is not restricted to pancreatic well-differentiated neuroendocrine neoplasms, but is also commonly found in well and poorly differentiated neuroendocrine neoplasms of extrapancreatic origin.
Agaimy A, Erlenbach-Wünsch K, Konukiewitz B, Schmitt AM, Rieker RJ, Vieth M, Kiesewetter F, Hartmann A, Zamboni G, Perren A, Klöppel G. Agaimy A, et al. Mod Pathol. 2013 Jul;26(7):995-1003. doi: 10.1038/modpathol.2013.40. Epub 2013 Mar 15. Mod Pathol. 2013. PMID: 23503646 Free article.
Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing.
Moskalev EA, Frohnauer J, Merkelbach-Bruse S, Schildhaus HU, Dimmler A, Schubert T, Boltze C, König H, Fuchs F, Sirbu H, Rieker RJ, Agaimy A, Hartmann A, Haller F. Moskalev EA, et al. Among authors: agaimy a. Lung Cancer. 2014 Jun;84(3):215-21. doi: 10.1016/j.lungcan.2014.03.002. Epub 2014 Mar 13. Lung Cancer. 2014. PMID: 24674157
Pattern of SMARCB1 (INI1) and SMARCA4 (BRG1) in poorly differentiated endometrioid adenocarcinoma of the uterus: analysis of a series with emphasis on a novel SMARCA4-deficient dedifferentiated rhabdoid variant.
Strehl JD, Wachter DL, Fiedler J, Heimerl E, Beckmann MW, Hartmann A, Agaimy A. Strehl JD, et al. Among authors: agaimy a. Ann Diagn Pathol. 2015 Aug;19(4):198-202. doi: 10.1016/j.anndiagpath.2015.04.001. Epub 2015 Apr 7. Ann Diagn Pathol. 2015. PMID: 25920939
SMARCA4-deficient Sinonasal Carcinoma.
Agaimy A, Weichert W. Agaimy A, et al. Head Neck Pathol. 2017 Dec;11(4):541-545. doi: 10.1007/s12105-017-0783-4. Epub 2017 Feb 7. Head Neck Pathol. 2017. PMID: 28176137 Free PMC article.
669 results