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Genetic markers of toxicity from capecitabine and other fluorouracil-based regimens: investigation in the QUASAR2 study, systematic review, and meta-analysis.
Rosmarin D, Palles C, Church D, Domingo E, Jones A, Johnstone E, Wang H, Love S, Julier P, Scudder C, Nicholson G, Gonzalez-Neira A, Martin M, Sargent D, Green E, McLeod H, Zanger UM, Schwab M, Braun M, Seymour M, Thompson L, Lacas B, Boige V, Ribelles N, Afzal S, Enghusen H, Jensen SA, Etienne-Grimaldi MC, Milano G, Wadelius M, Glimelius B, Garmo H, Gusella M, Lecomte T, Laurent-Puig P, Martinez-Balibrea E, Sharma R, Garcia-Foncillas J, Kleibl Z, Morel A, Pignon JP, Midgley R, Kerr D, Tomlinson I. Rosmarin D, et al. Among authors: afzal s. J Clin Oncol. 2014 Apr 1;32(10):1031-9. doi: 10.1200/JCO.2013.51.1857. Epub 2014 Mar 3. J Clin Oncol. 2014. PMID: 24590654 Free PMC article. Review.
Combinations of polymorphisms in genes involved in the 5-Fluorouracil metabolism pathway are associated with gastrointestinal toxicity in chemotherapy-treated colorectal cancer patients.
Afzal S, Gusella M, Vainer B, Vogel UB, Andersen JT, Broedbaek K, Petersen M, Jimenez-Solem E, Bertolaso L, Barile C, Padrini R, Pasini F, Jensen SA, Poulsen HE. Afzal S, et al. Clin Cancer Res. 2011 Jun 1;17(11):3822-9. doi: 10.1158/1078-0432.CCR-11-0304. Epub 2011 Apr 6. Clin Cancer Res. 2011. PMID: 21471424
The association of polymorphisms in 5-fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer.
Afzal S, Gusella M, Jensen SA, Vainer B, Vogel U, Andersen JT, Brødbæk K, Petersen M, Jimenez-Solem E, Adleff V, Budai B, Hitre E, Láng I, Orosz E, Bertolaso L, Barile C, Padrini R, Kralovánszky J, Pasini F, Poulsen HE. Afzal S, et al. Pharmacogenomics. 2011 Sep;12(9):1257-67. doi: 10.2217/pgs.11.83. Pharmacogenomics. 2011. PMID: 21919605
Data-driven assessment of the association of polymorphisms in 5-Fluorouracil metabolism genes with outcome in adjuvant treatment of colorectal cancer.
Sarac SB, Rasmussen CH, Afzal S, Thirstrup S, Jensen SA, Colding-Jørgensen M, Poulsen HE, Mosekilde E. Sarac SB, et al. Among authors: afzal s. Basic Clin Pharmacol Toxicol. 2012 Sep;111(3):189-97. doi: 10.1111/j.1742-7843.2012.00885.x. Epub 2012 Apr 16. Basic Clin Pharmacol Toxicol. 2012. PMID: 22448752 Free article.
Association of vitamin D with risk of type 2 diabetes: A Mendelian randomisation study in European and Chinese adults.
Lu L, Bennett DA, Millwood IY, Parish S, McCarthy MI, Mahajan A, Lin X, Bragg F, Guo Y, Holmes MV, Afzal S, Nordestgaard BG, Bian Z, Hill M, Walters RG, Li L, Chen Z, Clarke R. Lu L, et al. Among authors: afzal s. PLoS Med. 2018 May 2;15(5):e1002566. doi: 10.1371/journal.pmed.1002566. eCollection 2018 May. PLoS Med. 2018. PMID: 29718904 Free PMC article.
797 results