Afford S - Search Results

1

CX-4945 Induces Methuosis in Cholangiocarcinoma Cell Lines by a CK2-Independent Mechanism.

Lertsuwan J, Lertsuwan K, Sawasdichai A, Tasnawijitwong N, Lee KY, Kitchen P, Afford S, Gaston K, Jayaraman PS, Satayavivad J. Lertsuwan J, et al. Among authors: afford s. Cancers (Basel). 2018 Aug 23;10(9):283. doi: 10.3390/cancers10090283. Cancers (Basel). 2018. PMID: 30142881 Free PMC article.

2

A Runaway PRH/HHEX-Notch3-Positive Feedback Loop Drives Cholangiocarcinoma and Determines Response to CDK4/6 Inhibition.

Kitchen P, Lee KY, Clark D, Lau N, Lertsuwan J, Sawasdichai A, Satayavivad J, Oltean S, Afford S, Gaston K, Jayaraman PS. Kitchen P, et al. Among authors: afford s. Cancer Res. 2020 Feb 15;80(4):757-770. doi: 10.1158/0008-5472.CAN-19-0942. Epub 2019 Dec 16. Cancer Res. 2020. PMID: 31843982

3

Hepatitis C virus infection of cholangiocarcinoma cell lines.

Fletcher NF, Humphreys E, Jennings E, Osburn W, Lissauer S, Wilson GK, van IJzendoorn SCD, Baumert TF, Balfe P, Afford S, McKeating JA. Fletcher NF, et al. Among authors: afford s. J Gen Virol. 2015 Jun;96(Pt 6):1380-1388. doi: 10.1099/vir.0.000090. Epub 2015 Feb 20. J Gen Virol. 2015. PMID: 25701818 Free PMC article. Review.

4

Primary and malignant cholangiocytes undergo CD40 mediated Fas dependent apoptosis, but are insensitive to direct activation with exogenous Fas ligand.

Humphreys EH, Williams KT, Adams DH, Afford SC. Humphreys EH, et al. PLoS One. 2010 Nov 17;5(11):e14037. doi: 10.1371/journal.pone.0014037. PLoS One. 2010. PMID: 21103345 Free PMC article.

5

Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell-mediated liver damage.

Dunn C, Brunetto M, Reynolds G, Christophides T, Kennedy PT, Lampertico P, Das A, Lopes AR, Borrow P, Williams K, Humphreys E, Afford S, Adams DH, Bertoletti A, Maini MK. Dunn C, et al. Among authors: afford s. J Exp Med. 2007 Mar 19;204(3):667-80. doi: 10.1084/jem.20061287. Epub 2007 Mar 12. J Exp Med. 2007. PMID: 17353365 Free PMC article.

6

Quantitative assessment of the cell surface proteome to identify novel therapeutic targets in cholangiocarcinoma.

Stephenson B, Shimwell N, Humphreys E, Ward D, Adams D, Martin A, Afford S. Stephenson B, et al. Among authors: afford s. Lancet. 2015 Feb 26;385 Suppl 1:S94. doi: 10.1016/S0140-6736(15)60409-3. Lancet. 2015. PMID: 26312917

7

Vascular cell adhesion molecule 1 expression by biliary epithelium promotes persistence of inflammation by inhibiting effector T-cell apoptosis.

Afford SC, Humphreys EH, Reid DT, Russell CL, Banz VM, Oo Y, Vo T, Jenne C, Adams DH, Eksteen B. Afford SC, et al. Hepatology. 2014 May;59(5):1932-43. doi: 10.1002/hep.26965. Epub 2014 Mar 27. Hepatology. 2014. PMID: 24338559

8

Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation.

Wilhelm A, Shepherd EL, Amatucci A, Munir M, Reynolds G, Humphreys E, Resheq Y, Adams DH, Hübscher S, Burkly LC, Weston CJ, Afford SC. Wilhelm A, et al. Among authors: afford sc. J Pathol. 2016 May;239(1):109-21. doi: 10.1002/path.4707. Epub 2016 Mar 29. J Pathol. 2016. PMID: 26924336 Free PMC article.

9

Bidirectional Cross-Talk between Biliary Epithelium and Th17 Cells Promotes Local Th17 Expansion and Bile Duct Proliferation in Biliary Liver Diseases.

Jeffery HC, Hunter S, Humphreys EH, Bhogal R, Wawman RE, Birtwistle J, Atif M, Bagnal CJ, Rodriguez Blanco G, Richardson N, Warner S, Dunn WB, Afford SC, Adams DH, Oo YH. Jeffery HC, et al. Among authors: afford sc. J Immunol. 2019 Sep 1;203(5):1151-1159. doi: 10.4049/jimmunol.1800455. Epub 2019 Aug 7. J Immunol. 2019. PMID: 31391236 Free PMC article.

10

An effective protocol for pharmacological defatting of primary human hepatocytes which is non-toxic to cholangiocytes or intrahepatic endothelial cells.

Boteon YL, Wallace L, Boteon APCS, Mirza DF, Mergental H, Bhogal RH, Afford S. Boteon YL, et al. Among authors: afford s. PLoS One. 2018 Jul 25;13(7):e0201419. doi: 10.1371/journal.pone.0201419. eCollection 2018. PLoS One. 2018. PMID: 30044872 Free PMC article.

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