Adusumalli S - Search Results

1

Initial Pharmacological Characterization of a Major Hydroxy Metabolite of PF-5190457: Inverse Agonist Activity of PF-6870961 at the Ghrelin Receptor.

Deschaine SL, Hedegaard MA, Pince CL, Farokhnia M, Moose JE, Stock IA, Adusumalli S, Akhlaghi F, Hougland JL, Sulima A, Rice KC, Koob GF, Vendruscolo LF, Holst B, Leggio L. Deschaine SL, et al. Among authors: adusumalli s. J Pharmacol Exp Ther. 2023 Aug;386(2):117-128. doi: 10.1124/jpet.122.001393. Epub 2023 Jan 11. J Pharmacol Exp Ther. 2023. PMID: 36631279 Free PMC article.

2

Role of Molybdenum-Containing Enzymes in the Biotransformation of the Novel Ghrelin Receptor Inverse Agonist PF-5190457: A Reverse Translational Bed-to-Bench Approach.

Adusumalli S, Jamwal R, Obach RS, Ryder TF, Leggio L, Akhlaghi F. Adusumalli S, et al. Drug Metab Dispos. 2019 Aug;47(8):874-882. doi: 10.1124/dmd.119.087015. Epub 2019 Jun 10. Drug Metab Dispos. 2019. PMID: 31182423 Free PMC article. Clinical Trial.

3

Development and validation of an assay for a novel ghrelin receptor inverse agonist PF-5190457 and its major hydroxy metabolite (PF-6870961) by LC-MS/MS in human plasma.

Adusumalli S, Jamwal R, Leggio L, Akhlaghi F. Adusumalli S, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2019 Nov 1;1130-1131:121820. doi: 10.1016/j.jchromb.2019.121820. Epub 2019 Oct 8. J Chromatogr B Analyt Technol Biomed Life Sci. 2019. PMID: 31670107

4

Nonalcoholic Fatty Liver Disease and Diabetes Are Associated with Decreased CYP3A4 Protein Expression and Activity in Human Liver.

Jamwal R, de la Monte SM, Ogasawara K, Adusumalli S, Barlock BB, Akhlaghi F. Jamwal R, et al. Among authors: adusumalli s. Mol Pharm. 2018 Jul 2;15(7):2621-2632. doi: 10.1021/acs.molpharmaceut.8b00159. Epub 2018 Jun 11. Mol Pharm. 2018. PMID: 29792708 Free PMC article.

5

Multiplex and Label-Free Relative Quantification Approach for Studying Protein Abundance of Drug Metabolizing Enzymes in Human Liver Microsomes Using SWATH-MS.

Jamwal R, Barlock BJ, Adusumalli S, Ogasawara K, Simons BL, Akhlaghi F. Jamwal R, et al. Among authors: adusumalli s. J Proteome Res. 2017 Nov 3;16(11):4134-4143. doi: 10.1021/acs.jproteome.7b00505. Epub 2017 Oct 10. J Proteome Res. 2017. PMID: 28944677

6

Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1-Methyladenine and 3-Methylcytosine.

Tang Q, Cai A, Bian K, Chen F, Delaney JC, Adusumalli S, Bach AC 2nd, Akhlaghi F, Cho BP, Li D. Tang Q, et al. Among authors: adusumalli s. ACS Omega. 2017 Nov 30;2(11):8205-8212. doi: 10.1021/acsomega.7b01482. Epub 2017 Nov 20. ACS Omega. 2017. PMID: 29214236 Free PMC article.

7

Two Randomized Controlled Trials of Nudges to Encourage Referrals to Centralized Pharmacy Services for Evidence-Based Statin Initiation in High-Risk Patients: Rationale and Design of the SUPER LIPID Program.

Fanaroff AC, Huang Q, Clark K, Norton LA, Kellum WE, Eichelberger D, Wood JC, Bricker Z, Wood AGD, Kemmer G, Smith JI, Adusumalli S, Putt M, Volpp KGM. Fanaroff AC, et al. Among authors: adusumalli s. Am Heart J. 2024 Apr 26:S0002-8703(24)00099-1. doi: 10.1016/j.ahj.2024.04.013. Online ahead of print. Am Heart J. 2024. PMID: 38679189

8

Multiple Biomarkers to Predict Major Adverse Cardiovascular Events in Patients With Coronary Chronic Total Occlusions.

Adusumalli S, Mohebi R, McCarthy CP, Megaret CA, Rhyne RF, Jaffer FA, Januzzi JL. Adusumalli S, et al. medRxiv [Preprint]. 2023 Jul 23:2023.07.19.23292911. doi: 10.1101/2023.07.19.23292911. medRxiv. 2023. PMID: 37503157 Free PMC article. Preprint.

9

A Vision for the Future of Quality in Echocardiographic Reporting: The American Society of Echocardiography ImageGuideEcho Registry, Current and Future States.

Nagueh SF, Klein AL, Scherrer-Crosbie M, Fine NM, Kirkpatrick JN, Forsha DE, Nicoara A, Mackensen GB, Tilkemeier PL, Doukky R, Cheema B, Adusumalli S, Hill JC, Tanguturi VK, Ouyang D, Bdoyan SB, Strom JB. Nagueh SF, et al. Among authors: adusumalli s. J Am Soc Echocardiogr. 2023 Aug;36(8):805-811. doi: 10.1016/j.echo.2023.05.001. Epub 2023 May 31. J Am Soc Echocardiogr. 2023. PMID: 37256252 No abstract available.

10

Pluripotent stem cell-derived committed cardiac progenitors remuscularize damaged ischemic hearts and improve their function in pigs.

Yap L, Chong LY, Tan C, Adusumalli S, Seow M, Guo J, Cai Z, Loo SJ, Lim E, Tan RS, Grishina E, Soong PL, Lath N, Ye L, Petretto E, Tryggvason K. Yap L, et al. Among authors: adusumalli s. NPJ Regen Med. 2023 May 26;8(1):26. doi: 10.1038/s41536-023-00302-6. NPJ Regen Med. 2023. PMID: 37236990 Free PMC article.

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