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Page 1
Sensitivity and Resistance of Oncogenic RAS-Driven Tumors to Dual MEK and ERK Inhibition.
Catalano A, Adlesic M, Kaltenbacher T, Klar RFU, Albers J, Seidel P, Brandt LP, Hejhal T, Busenhart P, Röhner N, Zodel K, Fritsch K, Wild PJ, Duyster J, Fritsch R, Brummer T, Frew IJ. Catalano A, et al. Among authors: adlesic m. Cancers (Basel). 2021 Apr 13;13(8):1852. doi: 10.3390/cancers13081852. Cancers (Basel). 2021. PMID: 33924486 Free PMC article.
HIF-1α and HIF-2α differently regulate tumour development and inflammation of clear cell renal cell carcinoma in mice.
Hoefflin R, Harlander S, Schäfer S, Metzger P, Kuo F, Schönenberger D, Adlesic M, Peighambari A, Seidel P, Chen CY, Consenza-Contreras M, Jud A, Lahrmann B, Grabe N, Heide D, Uhl FM, Chan TA, Duyster J, Zeiser R, Schell C, Heikenwalder M, Schilling O, Hakimi AA, Boerries M, Frew IJ. Hoefflin R, et al. Among authors: adlesic m. Nat Commun. 2020 Aug 17;11(1):4111. doi: 10.1038/s41467-020-17873-3. Nat Commun. 2020. PMID: 32807776 Free PMC article.
Therapeutic Effects of Inhibition of Sphingosine-1-Phosphate Signaling in HIF-2α Inhibitor-Resistant Clear Cell Renal Cell Carcinoma.
Hoefflin R, Harlander S, Abhari BA, Peighambari A, Adlesic M, Seidel P, Zodel K, Haug S, Göcmen B, Li Y, Lahrmann B, Grabe N, Heide D, Boerries M, Köttgen A, Heikenwalder M, Frew IJ. Hoefflin R, et al. Among authors: adlesic m. Cancers (Basel). 2021 Sep 25;13(19):4801. doi: 10.3390/cancers13194801. Cancers (Basel). 2021. PMID: 34638286 Free PMC article.
ATR represents a therapeutic vulnerability in clear cell renal cell carcinoma.
Seidel P, Rubarth A, Zodel K, Peighambari A, Neumann F, Federkiel Y, Huang H, Hoefflin R, Adlesic M, Witt C, Hoffmann DJ, Metzger P, Lindemann RK, Zenke FT, Schell C, Boerries M, von Elverfeldt D, Reichardt W, Follo M, Albers J, Frew IJ. Seidel P, et al. Among authors: adlesic m. JCI Insight. 2022 Dec 22;7(24):e156087. doi: 10.1172/jci.insight.156087. JCI Insight. 2022. PMID: 36413415 Free PMC article.
Histamine in rheumatoid arthritis.
Adlesic M, Verdrengh M, Bokarewa M, Dahlberg L, Foster SJ, Tarkowski A. Adlesic M, et al. Scand J Immunol. 2007 Jun;65(6):530-7. doi: 10.1111/j.1365-3083.2007.01938.x. Scand J Immunol. 2007. PMID: 17523945 Free article.