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TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence.
Wu G, Yoshida N, Liu J, Zhang X, Xiong Y, Heavican-Foral TB, Mandato E, Liu H, Nelson GM, Yang L, Chen R, Donovan KA, Jones MK, Roshal M, Zhang Y, Xu R, Nirmal AJ, Jain S, Leahy C, Jones KL, Stevenson KE, Galasso N, Ganesan N, Chang T, Wu WC, Louissaint A, Debaize L, Yoon H, Dal Cin P, Chan WC, Ho Sui SJ, Ng SY, Feldman AL, Horwitz SM, Adelman K, Fischer ES, Chen CW, Weinstock DM, Brown M. Wu G, et al. Among authors: adelman k. Sci Transl Med. 2023 Sep 20;15(714):eadi7244. doi: 10.1126/scitranslmed.adi7244. Epub 2023 Sep 20. Sci Transl Med. 2023. PMID: 37729434 Free PMC article.
RNA polymerase is poised for activation across the genome.
Muse GW, Gilchrist DA, Nechaev S, Shah R, Parker JS, Grissom SF, Zeitlinger J, Adelman K. Muse GW, et al. Among authors: adelman k. Nat Genet. 2007 Dec;39(12):1507-11. doi: 10.1038/ng.2007.21. Epub 2007 Nov 11. Nat Genet. 2007. PMID: 17994021 Free PMC article.
Spt6 enhances the elongation rate of RNA polymerase II in vivo.
Ardehali MB, Yao J, Adelman K, Fuda NJ, Petesch SJ, Webb WW, Lis JT. Ardehali MB, et al. Among authors: adelman k. EMBO J. 2009 Apr 22;28(8):1067-77. doi: 10.1038/emboj.2009.56. Epub 2009 Mar 12. EMBO J. 2009. PMID: 19279664 Free PMC article.
SnapShot: Transcription regulation: pausing.
Fromm G, Gilchrist DA, Adelman K. Fromm G, et al. Among authors: adelman k. Cell. 2013 May 9;153(4):930-930.e1. doi: 10.1016/j.cell.2013.04.011. Cell. 2013. PMID: 23663787 Free article. No abstract available.
101 results