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Long-term potentiation and spatial memory training stimulate the hippocampal expression of RyR2 calcium release channels.
Valdés-Undurraga I, Lobos P, Sánchez-Robledo V, Arias-Cavieres A, SanMartín CD, Barrientos G, More J, Muñoz P, Paula-Lima AC, Hidalgo C, Adasme T. Valdés-Undurraga I, et al. Among authors: adasme t. Front Cell Neurosci. 2023 Mar 21;17:1132121. doi: 10.3389/fncel.2023.1132121. eCollection 2023. Front Cell Neurosci. 2023. PMID: 37025696 Free PMC article.
Amyloid β-peptide oligomers stimulate RyR-mediated Ca2+ release inducing mitochondrial fragmentation in hippocampal neurons and prevent RyR-mediated dendritic spine remodeling produced by BDNF.
Paula-Lima AC, Adasme T, SanMartín C, Sebollela A, Hetz C, Carrasco MA, Ferreira ST, Hidalgo C. Paula-Lima AC, et al. Among authors: adasme t. Antioxid Redox Signal. 2011 Apr 1;14(7):1209-23. doi: 10.1089/ars.2010.3287. Epub 2011 Jan 6. Antioxid Redox Signal. 2011. PMID: 20712397
High-frequency field stimulation of primary neurons enhances ryanodine receptor-mediated Ca2+ release and generates hydrogen peroxide, which jointly stimulate NF-κB activity.
Riquelme D, Alvarez A, Leal N, Adasme T, Espinoza I, Valdés JA, Troncoso N, Hartel S, Hidalgo J, Hidalgo C, Carrasco MA. Riquelme D, et al. Among authors: adasme t. Antioxid Redox Signal. 2011 Apr 1;14(7):1245-59. doi: 10.1089/ars.2010.3238. Epub 2010 Sep 13. Antioxid Redox Signal. 2011. PMID: 20836702
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