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Discovery of drug-omics associations in type 2 diabetes with generative deep-learning models.
Allesøe RL, Lundgaard AT, Hernández Medina R, Aguayo-Orozco A, Johansen J, Nissen JN, Brorsson C, Mazzoni G, Niu L, Biel JH, Leal Rodríguez C, Brasas V, Webel H, Benros ME, Pedersen AG, Chmura PJ, Jacobsen UP, Mari A, Koivula R, Mahajan A, Vinuela A, Tajes JF, Sharma S, Haid M, Hong MG, Musholt PB, De Masi F, Vogt J, Pedersen HK, Gudmundsdottir V, Jones A, Kennedy G, Bell J, Thomas EL, Frost G, Thomsen H, Hansen E, Hansen TH, Vestergaard H, Muilwijk M, Blom MT, 't Hart LM, Pattou F, Raverdy V, Brage S, Kokkola T, Heggie A, McEvoy D, Mourby M, Kaye J, Hattersley A, McDonald T, Ridderstråle M, Walker M, Forgie I, Giordano GN, Pavo I, Ruetten H, Pedersen O, Hansen T, Dermitzakis E, Franks PW, Schwenk JM, Adamski J, McCarthy MI, Pearson E, Banasik K, Rasmussen S, Brunak S; IMI DIRECT Consortium. Allesøe RL, et al. Among authors: adamski j. Nat Biotechnol. 2023 Mar;41(3):399-408. doi: 10.1038/s41587-022-01520-x. Epub 2023 Jan 2. Nat Biotechnol. 2023. PMID: 36593394 Free PMC article.
Recent advances in 17beta-hydroxysteroid dehydrogenases.
Prehn C, Möller G, Adamski J. Prehn C, et al. Among authors: adamski j. J Steroid Biochem Mol Biol. 2009 Mar;114(1-2):72-7. doi: 10.1016/j.jsbmb.2008.12.024. J Steroid Biochem Mol Biol. 2009. PMID: 19444936 Review.
Childhood obesity is associated with changes in the serum metabolite profile.
Wahl S, Yu Z, Kleber M, Singmann P, Holzapfel C, He Y, Mittelstrass K, Polonikov A, Prehn C, Römisch-Margl W, Adamski J, Suhre K, Grallert H, Illig T, Wang-Sattler R, Reinehr T. Wahl S, et al. Among authors: adamski j. Obes Facts. 2012;5(5):660-70. doi: 10.1159/000343204. Epub 2012 Oct 4. Obes Facts. 2012. PMID: 23108202 Free article.
Genetic variants including markers from the exome chip and metabolite traits of type 2 diabetes.
Jäger S, Wahl S, Kröger J, Sharma S, Hoffmann P, Floegel A, Pischon T, Prehn C, Adamski J, Müller-Nurasyid M, Waldenberger M, Strauch K, Peters A, Gieger C, Suhre K, Grallert H, Boeing H, Schulze MB, Meidtner K. Jäger S, et al. Among authors: adamski j. Sci Rep. 2017 Jul 20;7(1):6037. doi: 10.1038/s41598-017-06158-3. Sci Rep. 2017. PMID: 28729637 Free PMC article.
Endocrinology Meets Metabolomics: Achievements, Pitfalls, and Challenges.
Tokarz J, Haid M, Cecil A, Prehn C, Artati A, Möller G, Adamski J. Tokarz J, et al. Among authors: adamski j. Trends Endocrinol Metab. 2017 Oct;28(10):705-721. doi: 10.1016/j.tem.2017.07.001. Epub 2017 Aug 2. Trends Endocrinol Metab. 2017. PMID: 28780001 Review.
625 results