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Page 1
Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.
Hoang ON, Ermund A, Jaramillo AM, Fakih D, French CB, Flores JR, Karmouty-Quintana H, Magnusson JM, Fois G, Fauler M, Frick M, Braubach P, Hales JB, Kurten RC, Panettieri R, Vergara L, Ehre C, Adachi R, Tuvim MJ, Hansson GC, Dickey BF. Hoang ON, et al. Among authors: adachi r. Am J Respir Crit Care Med. 2022 Nov 1;206(9):1081-1095. doi: 10.1164/rccm.202202-0309OC. Am J Respir Crit Care Med. 2022. PMID: 35776514 Free PMC article.
Central role of Muc5ac expression in mucous metaplasia and its regulation by conserved 5' elements.
Young HW, Williams OW, Chandra D, Bellinghausen LK, Pérez G, Suárez A, Tuvim MJ, Roy MG, Alexander SN, Moghaddam SJ, Adachi R, Blackburn MR, Dickey BF, Evans CM. Young HW, et al. Among authors: adachi r. Am J Respir Cell Mol Biol. 2007 Sep;37(3):273-90. doi: 10.1165/rcmb.2005-0460OC. Epub 2007 Apr 26. Am J Respir Cell Mol Biol. 2007. PMID: 17463395 Free PMC article.
Stimulation of lung innate immunity protects against lethal pneumococcal pneumonia in mice.
Clement CG, Evans SE, Evans CM, Hawke D, Kobayashi R, Reynolds PR, Moghaddam SJ, Scott BL, Melicoff E, Adachi R, Dickey BF, Tuvim MJ. Clement CG, et al. Among authors: adachi r. Am J Respir Crit Care Med. 2008 Jun 15;177(12):1322-30. doi: 10.1164/rccm.200607-1038OC. Epub 2008 Apr 3. Am J Respir Crit Care Med. 2008. PMID: 18388354 Free PMC article.
Muc5b is required for airway defence.
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Roy MG, et al. Among authors: adachi r. Nature. 2014 Jan 16;505(7483):412-6. doi: 10.1038/nature12807. Epub 2013 Dec 8. Nature. 2014. PMID: 24317696 Free PMC article.
Different Munc18 proteins mediate baseline and stimulated airway mucin secretion.
Jaramillo AM, Piccotti L, Velasco WV, Delgado ASH, Azzegagh Z, Chung F, Nazeer U, Farooq J, Brenner J, Parker-Thornburg J, Scott BL, Evans CM, Adachi R, Burns AR, Kreda SM, Tuvim MJ, Dickey BF. Jaramillo AM, et al. Among authors: adachi r. JCI Insight. 2019 Mar 21;4(6):e124815. doi: 10.1172/jci.insight.124815. eCollection 2019 Mar 21. JCI Insight. 2019. PMID: 30721150 Free PMC article.
Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle-regulated exocytosis in mast cells.
Gutierrez BA, Chavez MA, Rodarte AI, Ramos MA, Dominguez A, Petrova Y, Davalos AJ, Costa RM, Elizondo R, Tuvim MJ, Dickey BF, Burns AR, Heidelberger R, Adachi R. Gutierrez BA, et al. Among authors: adachi r. J Biol Chem. 2018 May 11;293(19):7148-7159. doi: 10.1074/jbc.RA118.002455. Epub 2018 Mar 29. J Biol Chem. 2018. PMID: 29599294 Free PMC article.
259 results