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The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway.
Ogishima J, Taguchi A, Kawata A, Kawana K, Yoshida M, Yoshimatsu Y, Sato M, Nakamura H, Kawata Y, Nishijima A, Fujimoto A, Tomio K, Adachi K, Nagamatsu T, Oda K, Kiyono T, Osuga Y, Fujii T. Ogishima J, et al. Among authors: adachi k. BMC Cancer. 2018 Dec 3;18(1):1201. doi: 10.1186/s12885-018-4922-4. BMC Cancer. 2018. PMID: 30509235 Free PMC article.
Spheroid cancer stem cells display reprogrammed metabolism and obtain energy by actively running the tricarboxylic acid (TCA) cycle.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Takahashi J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: adachi k. Oncotarget. 2016 May 31;7(22):33297-305. doi: 10.18632/oncotarget.8947. Oncotarget. 2016. PMID: 27120812 Free PMC article.
Modification of the Tumor Microenvironment in KRAS or c-MYC-Induced Ovarian Cancer-Associated Peritonitis.
Yoshida M, Taguchi A, Kawana K, Adachi K, Kawata A, Ogishima J, Nakamura H, Fujimoto A, Sato M, Inoue T, Nishida H, Furuya H, Tomio K, Arimoto T, Koga K, Wada-Hiraike O, Oda K, Nagamatsu T, Kiyono T, Osuga Y, Fujii T. Yoshida M, et al. Among authors: adachi k. PLoS One. 2016 Aug 2;11(8):e0160330. doi: 10.1371/journal.pone.0160330. eCollection 2016. PLoS One. 2016. PMID: 27483433 Free PMC article.
Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer.
Nakamura H, Nagasaka K, Kawana K, Taguchi A, Uehara Y, Yoshida M, Sato M, Nishida H, Fujimoto A, Inoue T, Adachi K, Nagamatsu T, Arimoto T, Oda K, Osuga Y, Fujii T. Nakamura H, et al. Among authors: adachi k. BMC Cancer. 2016 Nov 17;16(1):897. doi: 10.1186/s12885-016-2929-2. BMC Cancer. 2016. PMID: 27855669 Free PMC article.
Targeting glutamine metabolism and the focal adhesion kinase additively inhibits the mammalian target of the rapamycin pathway in spheroid cancer stem-like properties of ovarian clear cell carcinoma in vitro.
Sato M, Kawana K, Adachi K, Fujimoto A, Yoshida M, Nakamura H, Nishida H, Inoue T, Taguchi A, Ogishima J, Eguchi S, Yamashita A, Tomio K, Wada-Hiraike O, Oda K, Nagamatsu T, Osuga Y, Fujii T. Sato M, et al. Among authors: adachi k. Int J Oncol. 2017 Apr;50(4):1431-1438. doi: 10.3892/ijo.2017.3891. Epub 2017 Feb 23. Int J Oncol. 2017. PMID: 28259988
Intraperitoneal neutrophils activated by KRAS-induced ovarian cancer exert antitumor effects by modulating adaptive immunity.
Yoshida M, Taguchi A, Kawana K, Ogishima J, Adachi K, Kawata A, Nakamura H, Sato M, Fujimoto A, Inoue T, Tomio K, Mori M, Nagamatsu T, Arimoto T, Koga K, Hiraike OW, Oda K, Kiyono T, Osuga Y, Fujii T. Yoshida M, et al. Among authors: adachi k. Int J Oncol. 2018 Oct;53(4):1580-1590. doi: 10.3892/ijo.2018.4504. Epub 2018 Jul 26. Int J Oncol. 2018. PMID: 30066851 Free PMC article.
Adjuvant effect of Japanese herbal medicines on the mucosal type 1 immune responses to human papillomavirus (HPV) E7 in mice immunized orally with Lactobacillus-based therapeutic HPV vaccine in a synergistic manner.
Taguchi A, Kawana K, Yokoyama T, Adachi K, Yamashita A, Tomio K, Kojima S, Oda K, Fujii T, Kozuma S. Taguchi A, et al. Among authors: adachi k. Vaccine. 2012 Aug 3;30(36):5368-72. doi: 10.1016/j.vaccine.2012.06.027. Epub 2012 Jun 21. Vaccine. 2012. PMID: 22727726
Matrix metalloproteinase (MMP)-9 in cancer-associated fibroblasts (CAFs) is suppressed by omega-3 polyunsaturated fatty acids in vitro and in vivo.
Taguchi A, Kawana K, Tomio K, Yamashita A, Isobe Y, Nagasaka K, Koga K, Inoue T, Nishida H, Kojima S, Adachi K, Matsumoto Y, Arimoto T, Wada-Hiraike O, Oda K, Kang JX, Arai H, Arita M, Osuga Y, Fujii T. Taguchi A, et al. Among authors: adachi k. PLoS One. 2014 Feb 27;9(2):e89605. doi: 10.1371/journal.pone.0089605. eCollection 2014. PLoS One. 2014. PMID: 24586907 Free PMC article.
Resveratrol Protects Against Pathological Preterm Birth by Suppression of Macrophage-Mediated Inflammation.
Furuya H, Taguchi A, Kawana K, Yamashita A, Inoue E, Yoshida M, Nakamura H, Fujimoto A, Inoue T, Sato M, Nishida H, Nagasaka K, Adachi K, Hoya M, Nagamatsu T, Wada-Hiraike O, Yamashita T, Osuga Y, Fujii T. Furuya H, et al. Among authors: adachi k. Reprod Sci. 2015 Dec;22(12):1561-8. doi: 10.1177/1933719115589413. Epub 2015 Jun 2. Reprod Sci. 2015. PMID: 26037299
2,242 results