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Page 1
Locally renewing resident synovial macrophages provide a protective barrier for the joint.
Culemann S, Grüneboom A, Nicolás-Ávila JÁ, Weidner D, Lämmle KF, Rothe T, Quintana JA, Kirchner P, Krljanac B, Eberhardt M, Ferrazzi F, Kretzschmar E, Schicht M, Fischer K, Gelse K, Faas M, Pfeifle R, Ackermann JA, Pachowsky M, Renner N, Simon D, Haseloff RF, Ekici AB, Bäuerle T, Blasig IE, Vera J, Voehringer D, Kleyer A, Paulsen F, Schett G, Hidalgo A, Krönke G. Culemann S, et al. Among authors: ackermann ja. Nature. 2019 Aug;572(7771):670-675. doi: 10.1038/s41586-019-1471-1. Epub 2019 Aug 7. Nature. 2019. PMID: 31391580 Free PMC article.
Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.
Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G. Pfeifle R, et al. Among authors: ackermann ja. Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7. Nat Immunol. 2017. PMID: 27820809 Free PMC article.
Enzymatic lipid oxidation by eosinophils propagates coagulation, hemostasis, and thrombotic disease.
Uderhardt S, Ackermann JA, Fillep T, Hammond VJ, Willeit J, Santer P, Mayr M, Biburger M, Miller M, Zellner KR, Stark K, Zarbock A, Rossaint J, Schubert I, Mielenz D, Dietel B, Raaz-Schrauder D, Ay C, Gremmel T, Thaler J, Heim C, Herrmann M, Collins PW, Schabbauer G, Mackman N, Voehringer D, Nadler JL, Lee JJ, Massberg S, Rauh M, Kiechl S, Schett G, O'Donnell VB, Krönke G. Uderhardt S, et al. Among authors: ackermann ja. J Exp Med. 2017 Jul 3;214(7):2121-2138. doi: 10.1084/jem.20161070. Epub 2017 May 31. J Exp Med. 2017. PMID: 28566277 Free PMC article.
Formation of atherosclerotic lesions is independent of eosinophils in male mice.
Hofheinz K, Seibert F, Ackermann JA, Dietel B, Tauchi M, Oszvar-Kozma M, Kühn H, Schett G, Binder CJ, Krönke G. Hofheinz K, et al. Among authors: ackermann ja. Atherosclerosis. 2020 Oct;311:67-72. doi: 10.1016/j.atherosclerosis.2020.08.030. Epub 2020 Sep 8. Atherosclerosis. 2020. PMID: 32947200
An advanced optical clearing protocol allows label-free detection of tissue necrosis via multiphoton microscopy in injured whole muscle.
Schneidereit D, Bröllochs A, Ritter P, Kreiß L, Mokhtari Z, Beilhack A, Krönke G, Ackermann JA, Faas M, Grüneboom A, Schürmann S, Friedrich O. Schneidereit D, et al. Among authors: ackermann ja. Theranostics. 2021 Jan 1;11(6):2876-2891. doi: 10.7150/thno.51558. eCollection 2021. Theranostics. 2021. PMID: 33456578 Free PMC article.
The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts.
Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp SJ, Walker KI, Ackermann JA, Chen X, Turner J, Zhu H, Seyler L, Euler M, Kirchner P, Krüger R, Ekici AB, Major T, Aust O, Weidner D, Fischer A, Andes FT, Stanojevic Z, Trajkovic V, Herrmann M, Korb-Pap A, Wank I, Hess A, Winter J, Wixler V, Distler J, Steiner G, Kiener HP, Frey B, Kling L, Raza K, Frey S, Kleyer A, Bäuerle T, Hughes TR, Grüneboom A, Steffen U, Krönke G, Croft AP, Filer A, Köhl J, Klein K, Buckley CD, Schett G, Mougiakakos D, Hoffmann MH. Friščić J, et al. Among authors: ackermann ja. Immunity. 2021 May 11;54(5):1002-1021.e10. doi: 10.1016/j.immuni.2021.03.003. Epub 2021 Mar 23. Immunity. 2021. PMID: 33761330 Free article.
IL-33-induced metabolic reprogramming controls the differentiation of alternatively activated macrophages and the resolution of inflammation.
Faas M, Ipseiz N, Ackermann J, Culemann S, Grüneboom A, Schröder F, Rothe T, Scholtysek C, Eberhardt M, Böttcher M, Kirchner P, Stoll C, Ekici A, Fuchs M, Kunz M, Weigmann B, Wirtz S, Lang R, Hofmann J, Vera J, Voehringer D, Michelucci A, Mougiakakos D, Uderhardt S, Schett G, Krönke G. Faas M, et al. Immunity. 2021 Nov 9;54(11):2531-2546.e5. doi: 10.1016/j.immuni.2021.09.010. Epub 2021 Oct 12. Immunity. 2021. PMID: 34644537 Free article.
Stunning of neutrophils accounts for the anti-inflammatory effects of clodronate liposomes.
Culemann S, Knab K, Euler M, Wegner A, Garibagaoglu H, Ackermann J, Fischer K, Kienhöfer D, Crainiciuc G, Hahn J, Grüneboom A, Nimmerjahn F, Uderhardt S, Hidalgo A, Schett G, Hoffmann MH, Krönke G. Culemann S, et al. J Exp Med. 2023 Jun 5;220(6):e20220525. doi: 10.1084/jem.20220525. Epub 2023 Mar 28. J Exp Med. 2023. PMID: 36976180 Free PMC article.
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