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SPRTN patient variants cause global-genome DNA-protein crosslink repair defects.
Nat Commun. 2023 Jan 21;14(1):352. doi: 10.1038/s41467-023-35988-1.
Nat Commun. 2023.
PMID: 36681662
Free PMC article.
DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease.
Reinking HK, Kang HS, Götz MJ, Li HY, Kieser A, Zhao S, Acampora AC, Weickert P, Fessler E, Jae LT, Sattler M, Stingele J.
Reinking HK, et al. Among authors: acampora ac.
Mol Cell. 2020 Oct 1;80(1):102-113.e6. doi: 10.1016/j.molcel.2020.08.003. Epub 2020 Aug 26.
Mol Cell. 2020.
PMID: 32853547
Free PMC article.
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A ubiquitin switch controls autocatalytic inactivation of the DNA-protein crosslink repair protease SPRTN.
Zhao S, Kieser A, Li HY, Reinking HK, Weickert P, Euteneuer S, Yaneva D, Acampora AC, Götz MJ, Feederle R, Stingele J.
Zhao S, et al. Among authors: acampora ac.
Nucleic Acids Res. 2021 Jan 25;49(2):902-915. doi: 10.1093/nar/gkaa1224.
Nucleic Acids Res. 2021.
PMID: 33348378
Free PMC article.
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Transcription-coupled repair of DNA-protein cross-links depends on CSA and CSB.
Carnie CJ, Acampora AC, Bader AS, Erdenebat C, Zhao S, Bitensky E, van den Heuvel D, Parnas A, Gupta V, D'Alessandro G, Sczaniecka-Clift M, Weickert P, Aygenli F, Götz MJ, Cordes J, Esain-Garcia I, Melidis L, Wondergem AP, Lam S, Robles MS, Balasubramanian S, Adar S, Luijsterburg MS, Jackson SP, Stingele J.
Carnie CJ, et al. Among authors: acampora ac.
Nat Cell Biol. 2024 May;26(5):797-810. doi: 10.1038/s41556-024-01391-1. Epub 2024 Apr 10.
Nat Cell Biol. 2024.
PMID: 38600235
Free PMC article.
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