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Distinct Hepatic PKA and CDK Signaling Pathways Control Activity-Independent Pyruvate Kinase Phosphorylation and Hepatic Glucose Production.
Gassaway BM, Cardone RL, Padyana AK, Petersen MC, Judd ET, Hayes S, Tong S, Barber KW, Apostolidi M, Abulizi A, Sheetz JB, Kshitiz, Aerni HR, Gross S, Kung C, Samuel VT, Shulman GI, Kibbey RG, Rinehart J. Gassaway BM, et al. Among authors: abulizi a. Cell Rep. 2019 Dec 10;29(11):3394-3404.e9. doi: 10.1016/j.celrep.2019.11.009. Cell Rep. 2019. PMID: 31825824 Free PMC article.
Metabolic control analysis of hepatic glycogen synthesis in vivo.
Nozaki Y, Petersen MC, Zhang D, Vatner DF, Perry RJ, Abulizi A, Haedersdal S, Zhang XM, Butrico GM, Samuel VT, Mason GF, Cline GW, Petersen KF, Rothman DL, Shulman GI. Nozaki Y, et al. Among authors: abulizi a. Proc Natl Acad Sci U S A. 2020 Apr 7;117(14):8166-8176. doi: 10.1073/pnas.1921694117. Epub 2020 Mar 18. Proc Natl Acad Sci U S A. 2020. PMID: 32188779 Free PMC article.
Adipose glucocorticoid action influences whole-body metabolism via modulation of hepatic insulin action.
Abulizi A, Camporez JP, Jurczak MJ, Høyer KF, Zhang D, Cline GW, Samuel VT, Shulman GI, Vatner DF. Abulizi A, et al. FASEB J. 2019 Jul;33(7):8174-8185. doi: 10.1096/fj.201802706R. Epub 2019 Mar 28. FASEB J. 2019. PMID: 30922125 Free PMC article.
Thus, we generated adipose tissue-specific glucocorticoid receptor-knockout (Ad-GcR(-/-)) mice to explore potential mechanisms. Ad-GcR(-/-) mice had a lower concentration of fasting plasma nonesterified fatty acids and less hepatic steatosis. ...Absence of adipose glucocor …
Thus, we generated adipose tissue-specific glucocorticoid receptor-knockout (Ad-GcR(-/-)) mice to explore potential mechanisms. Ad-GcR(-/-) …
Reduced intestinal lipid absorption and body weight-independent improvements in insulin sensitivity in high-fat diet-fed Park2 knockout mice.
Costa DK, Huckestein BR, Edmunds LR, Petersen MC, Nasiri A, Butrico GM, Abulizi A, Harmon DB, Lu C, Mantell BS, Hartman DJ, Camporez JP, O'Doherty RM, Cline GW, Shulman GI, Jurczak MJ. Costa DK, et al. Among authors: abulizi a. Am J Physiol Endocrinol Metab. 2016 Jul 1;311(1):E105-16. doi: 10.1152/ajpendo.00042.2016. Epub 2016 May 10. Am J Physiol Endocrinol Metab. 2016. PMID: 27166280 Free PMC article.
Insulin receptor Thr1160 phosphorylation mediates lipid-induced hepatic insulin resistance.
Petersen MC, Madiraju AK, Gassaway BM, Marcel M, Nasiri AR, Butrico G, Marcucci MJ, Zhang D, Abulizi A, Zhang XM, Philbrick W, Hubbard SR, Jurczak MJ, Samuel VT, Rinehart J, Shulman GI. Petersen MC, et al. Among authors: abulizi a. J Clin Invest. 2016 Nov 1;126(11):4361-4371. doi: 10.1172/JCI86013. Epub 2016 Oct 17. J Clin Invest. 2016. PMID: 27760050 Free PMC article.
A controlled-release mitochondrial protonophore reverses hypertriglyceridemia, nonalcoholic steatohepatitis, and diabetes in lipodystrophic mice.
Abulizi A, Perry RJ, Camporez JPG, Jurczak MJ, Petersen KF, Aspichueta P, Shulman GI. Abulizi A, et al. FASEB J. 2017 Jul;31(7):2916-2924. doi: 10.1096/fj.201700001R. Epub 2017 Mar 22. FASEB J. 2017. PMID: 28330852 Free PMC article.
Lipodystrophy is a rare disorder characterized by complete or partial loss of adipose tissue. ...-Abulizi, A., Perry, R. J., Camporez, J. P. G., Jurczak, M. J., Petersen, K. ...
Lipodystrophy is a rare disorder characterized by complete or partial loss of adipose tissue. ...-Abulizi, A., Perry, R …
[No title available]
[No authors listed] [No authors listed] PMID: 33455703
78 results