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Inhibition of amyloid fibrillation of γD-crystallin model peptide by the cochineal Carmine.
Int J Biol Macromol. 2021 Feb 1;169:342-351. doi: 10.1016/j.ijbiomac.2020.12.106. Epub 2020 Dec 18.
Int J Biol Macromol. 2021.
PMID: 33347930
An amyloidogenic hexapeptide from the cataract-associated γD-crystallin is a model for the full-length protein and is inhibited by naphthoquinone-tryptophan hybrids.
Abu-Hussien M, Viswanathan GK, Haj E, Paul A, Gazit E, Segal D.
Abu-Hussien M, et al.
Int J Biol Macromol. 2020 Aug 15;157:424-433. doi: 10.1016/j.ijbiomac.2020.04.079. Epub 2020 Apr 14.
Int J Biol Macromol. 2020.
PMID: 32302630
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The contribution of individual residues of an aggregative hexapeptide derived from the human γD-crystallin to its amyloidogenicity.
Abu-Hussien M, Viswanathan GK, Simhaev L, Paul A, Engel H, Gazit E, Segal D.
Abu-Hussien M, et al.
Int J Biol Macromol. 2022 Mar 15;201:182-192. doi: 10.1016/j.ijbiomac.2021.12.192. Epub 2022 Jan 6.
Int J Biol Macromol. 2022.
PMID: 34998884
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Cl-NQTrp Alleviates Tauopathy Symptoms in a Model Organism through the Inhibition of Tau Aggregation-Engendered Toxicity.
Frenkel-Pinter M, Tal S, Scherzer-Attali R, Abu-Hussien M, Alyagor I, Eisenbaum T, Gazit E, Segal D.
Frenkel-Pinter M, et al. Among authors: abu hussien m.
Neurodegener Dis. 2017;17(2-3):73-82. doi: 10.1159/000448518. Epub 2016 Oct 20.
Neurodegener Dis. 2017.
PMID: 27760426
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Differential effects of putative N-glycosylation sites in human Tau on Alzheimer's disease-related neurodegeneration.
Losev Y, Frenkel-Pinter M, Abu-Hussien M, Viswanathan GK, Elyashiv-Revivo D, Geries R, Khalaila I, Gazit E, Segal D.
Losev Y, et al. Among authors: abu hussien m.
Cell Mol Life Sci. 2021 Mar;78(5):2231-2245. doi: 10.1007/s00018-020-03643-3. Epub 2020 Sep 14.
Cell Mol Life Sci. 2021.
PMID: 32926180
Free PMC article.
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Naphthoquinone-Tryptophan Hybrid Inhibits Aggregation of the Tau-Derived Peptide PHF6 and Reduces Neurotoxicity.
Frenkel-Pinter M, Tal S, Scherzer-Attali R, Abu-Hussien M, Alyagor I, Eisenbaum T, Gazit E, Segal D.
Frenkel-Pinter M, et al. Among authors: abu hussien m.
J Alzheimers Dis. 2016;51(1):165-78. doi: 10.3233/JAD-150927.
J Alzheimers Dis. 2016.
PMID: 26836184
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