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Experimental design of D-α-tocopherol polyethylene glycol 1000 succinate stabilized bile salt based Nano-vesicles for improved cytotoxicity and bioavailability of colchicine binding site inhibitor Candidates: In Vitro, in silico, and pharmacokinetic studies.
Abo Elmaaty A, Al-Karmalawy AA, Nafie MS, Shamaa MM, Zaki I, Alnajjar R, Zakaria MY. Abo Elmaaty A, et al. Int J Pharm. 2023 Jun 10;640:122980. doi: 10.1016/j.ijpharm.2023.122980. Epub 2023 Apr 26. Int J Pharm. 2023. PMID: 37116601
Novel topoisomerase II/EGFR dual inhibitors: design, synthesis and docking studies of naphtho[2',3':4,5]thiazolo[3,2-a]pyrimidine hybrids as potential anticancer agents with apoptosis inducing activity.
Mourad MAE, Abo Elmaaty A, Zaki I, Mourad AAE, Hofni A, Khodir AE, Aboubakr EM, Elkamhawy A, Roh EJ, Al-Karmalawy AA. Mourad MAE, et al. Among authors: abo elmaaty a. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2205043. doi: 10.1080/14756366.2023.2205043. J Enzyme Inhib Med Chem. 2023. PMID: 37165800 Free PMC article.
Design and Synthesis of Novel 5-((3-(Trifluoromethyl)piperidin-1-yl)sulfonyl)indoline-2,3-dione Derivatives as Promising Antiviral Agents: In Vitro, In Silico, and Structure-Activity Relationship Studies.
Ezz Eldin RR, Saleh MA, Alwarsh SA, Rushdi A, Althoqapy AA, El Saeed HS, Abo Elmaaty A. Ezz Eldin RR, et al. Among authors: abo elmaaty a. Pharmaceuticals (Basel). 2023 Sep 4;16(9):1247. doi: 10.3390/ph16091247. Pharmaceuticals (Basel). 2023. PMID: 37765055 Free PMC article.
Nicotine exacerbates liver damage in a mice model of Ehrlich ascites carcinoma through shifting SOD/NF-κB/caspase-3 pathways: ameliorating role of Chlorella vulgaris.
Abu-Zeid EH, El-Hady EW, Ahmed GA, Abd-Elhakim YM, Ibrahim D, Abd-Allah NA, Arisha AH, Sobh MS, Abo-Elmaaty AMA. Abu-Zeid EH, et al. Among authors: abo elmaaty ama. Naunyn Schmiedebergs Arch Pharmacol. 2024 May 9. doi: 10.1007/s00210-024-03120-9. Online ahead of print. Naunyn Schmiedebergs Arch Pharmacol. 2024. PMID: 38722343
Multi-target rational design and synthesis of novel diphenyl-tethered pyrazolopyrimidines targeting EGFR and topoisomerase II with potential DNA intercalation and apoptosis induction.
Gaber AA, Abo Elmaaty A, Sharaky M, Mosa AA, Yahya Abdullah Alzahrani A, Shaaban S, Eldehna WM, Al-Karmalawy AA. Gaber AA, et al. Among authors: abo elmaaty a. Bioorg Chem. 2024 Apr;145:107223. doi: 10.1016/j.bioorg.2024.107223. Epub 2024 Feb 17. Bioorg Chem. 2024. PMID: 38387399
Benefits of Chlorella vulgaris against Cadmium Chloride-Induced Hepatic and Renal Toxicities via Restoring the Cellular Redox Homeostasis and Modulating Nrf2 and NF-KB Pathways in Male Rats.
Farag MR, Alagawany M, Mahdy EAA, El-Hady E, Abou-Zeid SM, Mawed SA, Azzam MM, Crescenzo G, Abo-Elmaaty AMA. Farag MR, et al. Among authors: abo elmaaty ama. Biomedicines. 2023 Aug 29;11(9):2414. doi: 10.3390/biomedicines11092414. Biomedicines. 2023. PMID: 37760855 Free PMC article.
33 results