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New dual 5-HT1A and 5-HT7 receptor ligands derived from SYA16263.
Ofori E, Onyameh EK, Gonela UM, Voshavar C, Bricker B, Swanson TL, Eshleman AJ, Schmachtenberg JL, Bloom SH, Janowsky AJ, Ablordeppey SY. Ofori E, et al. Among authors: ablordeppey sy. Eur J Med Chem. 2021 Mar 15;214:113243. doi: 10.1016/j.ejmech.2021.113243. Epub 2021 Feb 3. Eur J Med Chem. 2021. PMID: 33582388 Free PMC article.
Enantiomeric Separation, Absolute Configuration by X-ray Crystallographic Analysis, and Functional Evaluation of Enantiomers of the Dual Ligand, SYA0340 at 5-HT1A and 5-HT7A Receptors.
Bricker BA, Voshavar C, Onyameh EK, Gonela UM, Lin X, Swanson TL, Kozell LB, Schmachtenberg JL, Bloom SH, Janowsky AJ, Ablordeppey SY. Bricker BA, et al. Among authors: ablordeppey sy. ACS Omega. 2023 Jun 7;8(24):21736-21744. doi: 10.1021/acsomega.3c01283. eCollection 2023 Jun 20. ACS Omega. 2023. PMID: 37360419 Free PMC article.
New analogs of SYA013 as sigma-2 ligands with anticancer activity.
Asong G, Zhu XY, Bricker B, Andey T, Amissah F, Lamango N, Ablordeppey SY. Asong G, et al. Among authors: ablordeppey sy. Bioorg Med Chem. 2019 Jun 15;27(12):2629-2636. doi: 10.1016/j.bmc.2019.04.012. Epub 2019 Apr 8. Bioorg Med Chem. 2019. PMID: 30987780 Free PMC article.
Structure-activity relationship (SAR) and preliminary mode of action studies of 3-substituted benzylthioquinolinium iodide as anti-opportunistic infection agents.
Bolden S Jr, Zhu XY, Etukala JR, Boateng C, Mazu T, Flores-Rozas H, Jacob MR, Khan SI, Walker LA, Ablordeppey SY. Bolden S Jr, et al. Among authors: ablordeppey sy. Eur J Med Chem. 2013;70:130-42. doi: 10.1016/j.ejmech.2013.09.044. Epub 2013 Oct 5. Eur J Med Chem. 2013. PMID: 24141203 Free PMC article.
56 results