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cGAS-STING drives ageing-related inflammation and neurodegeneration.
Gulen MF, Samson N, Keller A, Schwabenland M, Liu C, Glück S, Thacker VV, Favre L, Mangeat B, Kroese LJ, Krimpenfort P, Prinz M, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Nature. 2023 Aug;620(7973):374-380. doi: 10.1038/s41586-023-06373-1. Epub 2023 Aug 2. Nature. 2023. PMID: 37532932 Free PMC article.
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: ablasser a. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
Inside Job: Viruses Transfer cGAMP between Cells.
Gulen MF, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Cell Host Microbe. 2015 Sep 9;18(3):263-5. doi: 10.1016/j.chom.2015.08.008. Cell Host Microbe. 2015. PMID: 26355209 Free article.
ReGLUation of cGAS.
Ablasser A. Ablasser A. Nat Immunol. 2016 Apr;17(4):347-9. doi: 10.1038/ni.3397. Nat Immunol. 2016. PMID: 27002833 No abstract available.
Signalling strength determines proapoptotic functions of STING.
Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w. Nat Commun. 2017. PMID: 28874664 Free PMC article.
Targeting STING with covalent small-molecule inhibitors.
Haag SM, Gulen MF, Reymond L, Gibelin A, Abrami L, Decout A, Heymann M, van der Goot FG, Turcatti G, Behrendt R, Ablasser A. Haag SM, et al. Among authors: ablasser a. Nature. 2018 Jul;559(7713):269-273. doi: 10.1038/s41586-018-0287-8. Epub 2018 Jul 4. Nature. 2018. PMID: 29973723
Innate immunosensing of DNA in cellular senescence.
Glück S, Ablasser A. Glück S, et al. Among authors: ablasser a. Curr Opin Immunol. 2019 Feb;56:31-36. doi: 10.1016/j.coi.2018.09.013. Epub 2018 Oct 5. Curr Opin Immunol. 2019. PMID: 30296662 Review.
60 results