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DNA hypomethylation leads to cGAS-induced autoinflammation in the epidermis.
Beck MA, Fischer H, Grabner LM, Groffics T, Winter M, Tangermann S, Meischel T, Zaussinger-Haas B, Wagner P, Fischer C, Folie C, Arand J, Schöfer C, Ramsahoye B, Lagger S, Machat G, Eisenwort G, Schneider S, Podhornik A, Kothmayer M, Reichart U, Glösmann M, Tamir I, Mildner M, Sheibani-Tezerji R, Kenner L, Petzelbauer P, Egger G, Sibilia M, Ablasser A, Seiser C. Beck MA, et al. Among authors: ablasser a. EMBO J. 2021 Nov 15;40(22):e108234. doi: 10.15252/embj.2021108234. Epub 2021 Sep 29. EMBO J. 2021. PMID: 34586646 Free PMC article.
The role of cGAS in innate immunity and beyond.
Ablasser A, Gulen MF. Ablasser A, et al. J Mol Med (Berl). 2016 Oct;94(10):1085-1093. doi: 10.1007/s00109-016-1423-2. Epub 2016 May 6. J Mol Med (Berl). 2016. PMID: 27154323 Review.
Interplay of cGAS with chromatin.
Wischnewski M, Ablasser A. Wischnewski M, et al. Among authors: ablasser a. Trends Biochem Sci. 2021 Oct;46(10):822-831. doi: 10.1016/j.tibs.2021.05.011. Epub 2021 Jun 29. Trends Biochem Sci. 2021. PMID: 34215510 Review.
The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.
Domizio JD, Gulen MF, Saidoune F, Thacker VV, Yatim A, Sharma K, Nass T, Guenova E, Schaller M, Conrad C, Goepfert C, de Leval L, Garnier CV, Berezowska S, Dubois A, Gilliet M, Ablasser A. Domizio JD, et al. Among authors: ablasser a. Nature. 2022 Mar;603(7899):145-151. doi: 10.1038/s41586-022-04421-w. Epub 2022 Jan 19. Nature. 2022. PMID: 35045565 Free PMC article.
Emerging dimensions of cellular cGAS-STING signaling.
Guey B, Ablasser A. Guey B, et al. Among authors: ablasser a. Curr Opin Immunol. 2022 Feb;74:164-171. doi: 10.1016/j.coi.2022.01.004. Epub 2022 Feb 3. Curr Opin Immunol. 2022. PMID: 35124516 Review.
The cGAS-STING pathway and cancer.
Samson N, Ablasser A. Samson N, et al. Among authors: ablasser a. Nat Cancer. 2022 Dec;3(12):1452-1463. doi: 10.1038/s43018-022-00468-w. Epub 2022 Dec 12. Nat Cancer. 2022. PMID: 36510011 Review.
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: ablasser a. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
60 results