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A dysbiotic microbiome triggers TH17 cells to mediate oral mucosal immunopathology in mice and humans.
Dutzan N, Kajikawa T, Abusleme L, Greenwell-Wild T, Zuazo CE, Ikeuchi T, Brenchley L, Abe T, Hurabielle C, Martin D, Morell RJ, Freeman AF, Lazarevic V, Trinchieri G, Diaz PI, Holland SM, Belkaid Y, Hajishengallis G, Moutsopoulos NM. Dutzan N, et al. Among authors: abe t. Sci Transl Med. 2018 Oct 17;10(463):eaat0797. doi: 10.1126/scitranslmed.aat0797. Sci Transl Med. 2018. PMID: 30333238 Free PMC article. Clinical Trial.
Defective neutrophil recruitment in leukocyte adhesion deficiency type I disease causes local IL-17-driven inflammatory bone loss.
Moutsopoulos NM, Konkel J, Sarmadi M, Eskan MA, Wild T, Dutzan N, Abusleme L, Zenobia C, Hosur KB, Abe T, Uzel G, Chen W, Chavakis T, Holland SM, Hajishengallis G. Moutsopoulos NM, et al. Among authors: abe t. Sci Transl Med. 2014 Mar 26;6(229):229ra40. doi: 10.1126/scitranslmed.3007696. Sci Transl Med. 2014. PMID: 24670684 Free PMC article.
Role of complement in host-microbe homeostasis of the periodontium.
Hajishengallis G, Abe T, Maekawa T, Hajishengallis E, Lambris JD. Hajishengallis G, et al. Among authors: abe t. Semin Immunol. 2013 Feb;25(1):65-72. doi: 10.1016/j.smim.2013.04.004. Epub 2013 May 16. Semin Immunol. 2013. PMID: 23684627 Free PMC article. Review.
8,903 results