Abay ET - Search Results

1

Syntheses and in Vitro Antiplasmodial Activity of Aminoalkylated Chalcones and Analogues.

Wilhelm A, Kendrekar P, Noreljaleel AE, Abay ET, Bonnet SL, Wiesner L, de Kock C, Swart KJ, van der Westhuizen JH. Wilhelm A, et al. Among authors: abay et. J Nat Prod. 2015 Aug 28;78(8):1848-58. doi: 10.1021/acs.jnatprod.5b00114. Epub 2015 Aug 3. J Nat Prod. 2015. PMID: 26235033

2

In Vitro and In Vivo Pharmacokinetics of Aminoalkylated Diarylpropanes NP085 and NP102.

Gibhard L, Pravin K, Abay E, Wilhelm A, Swart K, Lawrence N, Khoury R, van der Westhuizen J, Smith P, Wiesner L. Gibhard L, et al. Antimicrob Agents Chemother. 2016 Apr 22;60(5):3065-9. doi: 10.1128/AAC.02104-15. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26953201 Free PMC article.

3

The development and validation of an LC-MS/MS method for the determination of a new anti-malarial compound (TK900D) in human whole blood and its application to pharmacokinetic studies in mice.

Abay ET, van der Westhuizen JH, Swart KJ, Gibhard L, Tukulula M, Chibale K, Wiesner L. Abay ET, et al. Malar J. 2014 Jan 31;13:42. doi: 10.1186/1475-2875-13-42. Malar J. 2014. PMID: 24484513 Free PMC article.

4

Efficacy and pharmacokinetic evaluation of a novel anti-malarial compound (NP046) in a mouse model.

Abay ET, van der Westuizen JH, Swart KJ, Gibhard L, Lawrence N, Dambuza N, Wilhelm A, Pravin K, Wiesner L. Abay ET, et al. Malar J. 2015 Jan 6;14:8. doi: 10.1186/1475-2875-14-8. Malar J. 2015. PMID: 25563929 Free PMC article.

5

Synthesis and in vitro and in vivo pharmacological evaluation of new 4-aminoquinoline-based compounds.

Tukulula M, Njoroge M, Abay ET, Mugumbate GC, Wiesner L, Taylor D, Gibhard L, Norman J, Swart KJ, Gut J, Rosenthal PJ, Barteau S, Streckfuss J, Kameni-Tcheudji J, Chibale K. Tukulula M, et al. Among authors: abay et. ACS Med Chem Lett. 2013 Oct 1;4(12):1198-202. doi: 10.1021/ml400311r. eCollection 2013 Dec 12. ACS Med Chem Lett. 2013. PMID: 24900630 Free PMC article.

6

Investigating Sulfoxide-to-Sulfone Conversion as a Prodrug Strategy for a Phosphatidylinositol 4-Kinase Inhibitor in a Humanized Mouse Model of Malaria.

Gibhard L, Njoroge M, Paquet T, Brunschwig C, Taylor D, Lawrence N, Abay E, Wittlin S, Wiesner L, Street LJ, Chibale K, Basarab GS. Gibhard L, et al. Antimicrob Agents Chemother. 2018 Nov 26;62(12):e00261-18. doi: 10.1128/AAC.00261-18. Print 2018 Dec. Antimicrob Agents Chemother. 2018. PMID: 30249687 Free PMC article.

7

The In Vitro and In Vivo Effects of Hypoxis hemerocallidea on Indinavir Pharmacokinetics: Modulation of Efflux.

Havenga K, Abay E, Wiesner L, Viljoen A, Steyn D, Hamman J. Havenga K, et al. Planta Med. 2018 Aug;84(12-13):895-901. doi: 10.1055/a-0607-2743. Epub 2018 Apr 19. Planta Med. 2018. PMID: 29672818 Free article.

8

Evaluation of Isolated Fractions of Aloe vera Gel Materials on Indinavir Pharmacokinetics: In vitro and in vivo Studies.

Wallis L, Malan M, Gouws C, Steyn D, Ellis S, Abay E, Wiesner L, Otto DP, Hamman J. Wallis L, et al. Curr Drug Deliv. 2016;13(3):471-80. doi: 10.2174/1567201813888160302163208. Curr Drug Deliv. 2016. PMID: 26568138

9

Herb-Drug Pharmacokinetic Interactions: Transport and Metabolism of Indinavir in the Presence of Selected Herbal Products.

Calitz C, Gouws C, Viljoen J, Steenekamp J, Wiesner L, Abay E, Hamman J. Calitz C, et al. Molecules. 2015 Dec 10;20(12):22113-27. doi: 10.3390/molecules201219838. Molecules. 2015. PMID: 26690396 Free PMC article.

10

UCT943, a Next-Generation Plasmodium falciparum PI4K Inhibitor Preclinical Candidate for the Treatment of Malaria.

Brunschwig C, Lawrence N, Taylor D, Abay E, Njoroge M, Basarab GS, Le Manach C, Paquet T, Cabrera DG, Nchinda AT, de Kock C, Wiesner L, Denti P, Waterson D, Blasco B, Leroy D, Witty MJ, Donini C, Duffy J, Wittlin S, White KL, Charman SA, Jiménez-Díaz MB, Angulo-Barturen I, Herreros E, Gamo FJ, Rochford R, Mancama D, Coetzer TL, van der Watt ME, Reader J, Birkholtz LM, Marsh KC, Solapure SM, Burke JE, McPhail JA, Vanaerschot M, Fidock DA, Fish PV, Siegl P, Smith DA, Wirjanata G, Noviyanti R, Price RN, Marfurt J, Silue KD, Street LJ, Chibale K. Brunschwig C, et al. Antimicrob Agents Chemother. 2018 Aug 27;62(9):e00012-18. doi: 10.1128/AAC.00012-18. Print 2018 Sep. Antimicrob Agents Chemother. 2018. PMID: 29941635 Free PMC article.

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