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Optimising pyrazinamide for the treatment of tuberculosis.
Zhang N, Savic RM, Boeree MJ, Peloquin CA, Weiner M, Heinrich N, Bliven-Sizemore E, Phillips PPJ, Hoelscher M, Whitworth W, Morlock G, Posey J, Stout JE, Mac Kenzie W, Aarnoutse R, Dooley KE; Tuberculosis Trials Consortium (TBTC) and Pan African Consortium for the Evaluation of Antituberculosis Antibiotics (PanACEA) Networks. Zhang N, et al. Among authors: aarnoutse r. Eur Respir J. 2021 Jul 20;58(1):2002013. doi: 10.1183/13993003.02013-2020. Print 2021 Jul. Eur Respir J. 2021. PMID: 33542052 Free PMC article. Clinical Trial.
Therapeutic drug monitoring in the treatment of tuberculosis patients.
Magis-Escurra C, van den Boogaard J, Ijdema D, Boeree M, Aarnoutse R. Magis-Escurra C, et al. Among authors: aarnoutse r. Pulm Pharmacol Ther. 2012 Feb;25(1):83-6. doi: 10.1016/j.pupt.2011.12.001. Epub 2011 Dec 11. Pulm Pharmacol Ther. 2012. PMID: 22179055
Direct comparison of Xpert MTB/RIF assay with liquid and solid mycobacterial culture for quantification of early bactericidal activity.
Kayigire XA, Friedrich SO, Venter A, Dawson R, Gillespie SH, Boeree MJ, Heinrich N, Hoelscher M, Diacon AH; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics. Kayigire XA, et al. J Clin Microbiol. 2013 Jun;51(6):1894-8. doi: 10.1128/JCM.03290-12. Epub 2013 Apr 17. J Clin Microbiol. 2013. PMID: 23596237 Free PMC article.
The molecular bacterial load assay replaces solid culture for measuring early bactericidal response to antituberculosis treatment.
Honeyborne I, Mtafya B, Phillips PP, Hoelscher M, Ntinginya EN, Kohlenberg A, Rachow A, Rojas-Ponce G, McHugh TD, Heinrich N; Pan African Consortium for the Evaluation of Anti-tuberculosis Antibiotics. Honeyborne I, et al. J Clin Microbiol. 2014 Aug;52(8):3064-7. doi: 10.1128/JCM.01128-14. Epub 2014 May 28. J Clin Microbiol. 2014. PMID: 24871215 Free PMC article.
The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations.
Bowness R, Boeree MJ, Aarnoutse R, Dawson R, Diacon A, Mangu C, Heinrich N, Ntinginya NE, Kohlenberg A, Mtafya B, Phillips PP, Rachow A, Plemper van Balen G, Gillespie SH. Bowness R, et al. Among authors: aarnoutse r. J Antimicrob Chemother. 2015 Feb;70(2):448-55. doi: 10.1093/jac/dku415. Epub 2014 Oct 25. J Antimicrob Chemother. 2015. PMID: 25344806
239 results