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IL-37 requires the receptors IL-18Rα and IL-1R8 (SIGIRR) to carry out its multifaceted anti-inflammatory program upon innate signal transduction.
Nold-Petry CA, Lo CY, Rudloff I, Elgass KD, Li S, Gantier MP, Lotz-Havla AS, Gersting SW, Cho SX, Lao JC, Ellisdon AM, Rotter B, Azam T, Mangan NE, Rossello FJ, Whisstock JC, Bufler P, Garlanda C, Mantovani A, Dinarello CA, Nold MF. Nold-Petry CA, et al. Nat Immunol. 2015 Apr;16(4):354-65. doi: 10.1038/ni.3103. Epub 2015 Mar 2. Nat Immunol. 2015. PMID: 25729923
Inflammasome-independent regulation of IL-1-family cytokines.
Netea MG, van de Veerdonk FL, van der Meer JW, Dinarello CA, Joosten LA. Netea MG, et al. Annu Rev Immunol. 2015;33:49-77. doi: 10.1146/annurev-immunol-032414-112306. Epub 2014 Dec 10. Annu Rev Immunol. 2015. PMID: 25493334 Review.
IL-37 inhibits inflammasome activation and disease severity in murine aspergillosis.
Moretti S, Bozza S, Oikonomou V, Renga G, Casagrande A, Iannitti RG, Puccetti M, Garlanda C, Kim S, Li S, van de Veerdonk FL, Dinarello CA, Romani L. Moretti S, et al. PLoS Pathog. 2014 Nov 6;10(11):e1004462. doi: 10.1371/journal.ppat.1004462. eCollection 2014 Nov. PLoS Pathog. 2014. PMID: 25375146 Free PMC article.
23 results