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2016 1
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Page 1
Dose escalation and expansion cohorts in patients with advanced breast cancer in a Phase I study of the CDK7-inhibitor samuraciclib.
Coombes RC, Howell S, Lord SR, Kenny L, Mansi J, Mitri Z, Palmieri C, Chap LI, Richards P, Gradishar W, Sardesai S, Melear J, O'Shaughnessy J, Ward P, Chalasani P, Arkenau T, Baird RD, Jeselsohn R, Ali S, Clack G, Bahl A, McIntosh S, Krebs MG. Coombes RC, et al. Nat Commun. 2023 Jul 24;14(1):4444. doi: 10.1038/s41467-023-40061-y. Nat Commun. 2023. PMID: 37488191 Free PMC article. Clinical Trial.
Genome engineering for estrogen receptor mutations reveals differential responses to anti-estrogens and new prognostic gene signatures for breast cancer.
Harrod A, Lai CF, Goldsbrough I, Simmons GM, Oppermans N, Santos DB, Győrffy B, Allsopp RC, Toghill BJ, Balachandran K, Lawson M, Morrow CJ, Surakala M, Carnevalli LS, Zhang P, Guttery DS, Shaw JA, Coombes RC, Buluwela L, Ali S. Harrod A, et al. Oncogene. 2022 Oct;41(44):4905-4915. doi: 10.1038/s41388-022-02483-8. Epub 2022 Oct 5. Oncogene. 2022. PMID: 36198774 Free PMC article.
CDK7 inhibitors as anticancer drugs.
Sava GP, Fan H, Coombes RC, Buluwela L, Ali S. Sava GP, et al. Cancer Metastasis Rev. 2020 Sep;39(3):805-823. doi: 10.1007/s10555-020-09885-8. Cancer Metastasis Rev. 2020. PMID: 32385714 Free PMC article. Review.
High-resolution label-free 3D mapping of extracellular pH of single living cells.
Zhang Y, Takahashi Y, Hong SP, Liu F, Bednarska J, Goff PS, Novak P, Shevchuk A, Gopal S, Barozzi I, Magnani L, Sakai H, Suguru Y, Fujii T, Erofeev A, Gorelkin P, Majouga A, Weiss DJ, Edwards C, Ivanov AP, Klenerman D, Sviderskaya EV, Edel JB, Korchev Y. Zhang Y, et al. Nat Commun. 2019 Dec 6;10(1):5610. doi: 10.1038/s41467-019-13535-1. Nat Commun. 2019. PMID: 31811139 Free PMC article.
18 results