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Expectant Management or Early Ibuprofen for Patent Ductus Arteriosus.
N Engl J Med. 2023 Mar 16;388(11):980-990. doi: 10.1056/NEJMoa2207418. Epub 2022 Dec 6.
N Engl J Med. 2023.
PMID: 36477458
Clinical Trial.
Multi-centre, randomised non-inferiority trial of early treatment versus expectant management of patent ductus arteriosus in preterm infants (the BeNeDuctus trial): statistical analysis plan.
Hundscheid T, Donders R, Onland W, Kooi EMW, Vijlbrief DC, de Vries WB, Nuytemans DHGM, van Overmeire B, Mulder AL, de Boode WP; BeNeDuctus trial study group.
Hundscheid T, et al.
Trials. 2021 Sep 15;22(1):627. doi: 10.1186/s13063-021-05594-x.
Trials. 2021.
PMID: 34526095
Free PMC article.
Clinical Trial.
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