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Page 1
Embryo model completes gastrulation to neurulation and organogenesis.
Amadei G, Handford CE, Qiu C, De Jonghe J, Greenfeld H, Tran M, Martin BK, Chen DY, Aguilera-Castrejon A, Hanna JH, Elowitz MB, Hollfelder F, Shendure J, Glover DM, Zernicka-Goetz M. Amadei G, et al. Nature. 2022 Oct;610(7930):143-153. doi: 10.1038/s41586-022-05246-3. Epub 2022 Aug 25. Nature. 2022. PMID: 36007540 Free PMC article.
An in vitro stem cell model of human epiblast and yolk sac interaction.
Mackinlay KM, Weatherbee BA, Souza Rosa V, Handford CE, Hudson G, Coorens T, Pereira LV, Behjati S, Vallier L, Shahbazi MN, Zernicka-Goetz M. Mackinlay KM, et al. Elife. 2021 Aug 17;10:e63930. doi: 10.7554/eLife.63930. Elife. 2021. PMID: 34403333 Free PMC article.
Epigenetic remodelling licences adult cholangiocytes for organoid formation and liver regeneration.
Aloia L, McKie MA, Vernaz G, Cordero-Espinoza L, Aleksieva N, van den Ameele J, Antonica F, Font-Cunill B, Raven A, Aiese Cigliano R, Belenguer G, Mort RL, Brand AH, Zernicka-Goetz M, Forbes SJ, Miska EA, Huch M. Aloia L, et al. Nat Cell Biol. 2019 Nov;21(11):1321-1333. doi: 10.1038/s41556-019-0402-6. Epub 2019 Nov 4. Nat Cell Biol. 2019. PMID: 31685987 Free PMC article.
Pluripotent state transitions coordinate morphogenesis in mouse and human embryos.
Shahbazi MN, Scialdone A, Skorupska N, Weberling A, Recher G, Zhu M, Jedrusik A, Devito LG, Noli L, Macaulay IC, Buecker C, Khalaf Y, Ilic D, Voet T, Marioni JC, Zernicka-Goetz M. Shahbazi MN, et al. Nature. 2017 Dec 14;552(7684):239-243. doi: 10.1038/nature24675. Epub 2017 Nov 29. Nature. 2017. PMID: 29186120 Free PMC article.