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Assessing the Immunomodulatory Effect of Size on the Uptake and Immunogenicity of Influenza- and Hepatitis B Subunit Vaccines In Vitro.
Heida R, Born PA, Tapia-Calle G, Frijlink HW, Salvati A, Huckriede ALW, Hinrichs WLJ. Heida R, et al. Pharmaceuticals (Basel). 2022 Jul 18;15(7):887. doi: 10.3390/ph15070887. Pharmaceuticals (Basel). 2022. PMID: 35890185 Free PMC article.
Viral subunit vaccines are a safer and more tolerable alternative to whole inactivated virus vaccines. ...Conjugation of both antigens to particles significantly increased their uptake by Mo-DCs. Moreover, both the 500 nm and 3 mum influenza conjugates induce …
Viral subunit vaccines are a safer and more tolerable alternative to whole inactivated virus vaccines. ...Conjugation of both …
A PBMC-Based System to Assess Human T Cell Responses to Influenza Vaccine Candidates In Vitro.
Tapia-Calle G, Born PA, Koutsoumpli G, Gonzalez-Rodriguez MI, Hinrichs WLJ, Huckriede ALW. Tapia-Calle G, et al. Vaccines (Basel). 2019 Nov 13;7(4):181. doi: 10.3390/vaccines7040181. Vaccines (Basel). 2019. PMID: 31766202 Free PMC article.
Alternative assay systems that can add to the screening and evaluation of functional characteristics of vaccines in a human context before embarking on costly clinical trials are therefore urgently needed. In this study, we have established an in vitro system consisting of …
Alternative assay systems that can add to the screening and evaluation of functional characteristics of vaccines in a human context b …