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Epigenetic remodeling to improve the efficacy of immunotherapy in human glioblastoma: pre-clinical evidence for development of new immunotherapy approaches.
Lofiego MF, Piazzini F, Caruso FP, Marzani F, Solmonese L, Bello E, Celesti F, Costa MC, Noviello T, Mortarini R, Anichini A, Ceccarelli M, Coral S, Di Giacomo AM, Maio M, Covre A; EPigenetic Immune-oncology Consortium Airc (EPICA) investigators. Lofiego MF, et al. J Transl Med. 2024 Mar 1;22(1):223. doi: 10.1186/s12967-024-05040-x. J Transl Med. 2024. PMID: 38429759 Free PMC article.
Guadecitabine increases response to combined anti-CTLA-4 and anti-PD-1 treatment in mouse melanoma in vivo by controlling T-cells, myeloid derived suppressor and NK cells.
Amaro A, Reggiani F, Fenoglio D, Gangemi R, Tosi A, Parodi A, Banelli B, Rigo V, Mastracci L, Grillo F, Cereghetti A, Tastanova A, Ghosh A, Sallustio F, Emionite L, Daga A, Altosole T, Filaci G, Rosato A, Levesque M, Maio M, Pfeffer U, Croce M; EPigenetic Immune-oncology Consortium Airc (EPICA) consortium. Amaro A, et al. J Exp Clin Cancer Res. 2023 Mar 18;42(1):67. doi: 10.1186/s13046-023-02628-x. J Exp Clin Cancer Res. 2023. PMID: 36934257 Free PMC article.
Landscape of immune-related signatures induced by targeting of different epigenetic regulators in melanoma: implications for immunotherapy.
Anichini A, Molla A, Nicolini G, Perotti VE, Sgambelluri F, Covre A, Fazio C, Lofiego MF, Di Giacomo AM, Coral S, Manca A, Sini MC, Pisano M, Noviello T, Caruso F, Brich S, Pruneri G, Maurichi A, Santinami M, Ceccarelli M, Palmieri G, Maio M, Mortarini R; EPigenetic Immune-oncology Consortium AIRC (EPICA) investigators. Anichini A, et al. J Exp Clin Cancer Res. 2022 Nov 17;41(1):325. doi: 10.1186/s13046-022-02529-5. J Exp Clin Cancer Res. 2022. PMID: 36397155 Free PMC article.
Epigenetic Immune Remodeling of Mesothelioma Cells: A New Strategy to Improve the Efficacy of Immunotherapy.
Lofiego MF, Cannito S, Fazio C, Piazzini F, Cutaia O, Solmonese L, Marzani F, Chiarucci C, Di Giacomo AM, Calabrò L, Coral S, Maio M, Covre A, On Behalf Of The EPigenetic Immune-Oncology Consortium Airc Epica Investigators. Lofiego MF, et al. Epigenomes. 2021 Dec 14;5(4):27. doi: 10.3390/epigenomes5040027. Epigenomes. 2021. PMID: 34968251 Free PMC article.
NGS-Based Analysis of Atypical Deep Penetrating Nevi.
Manca A, Sini MC, Cesinaro AM, Portelli F, Urso C, Lentini M, Cardia R, Alos L, Cook M, Simi S, Paliogiannis P, De Giorgi V, Cossu A, Palmieri G, Massi D. Manca A, et al. Cancers (Basel). 2021 Jun 19;13(12):3066. doi: 10.3390/cancers13123066. Cancers (Basel). 2021. PMID: 34205480 Free PMC article.
Quality assessment of a clinical next-generation sequencing melanoma panel within the Italian Melanoma Intergroup (IMI).
Vanni I, Casula M, Pastorino L, Manca A, Dalmasso B, Andreotti V, Pisano M, Colombino M; Italian Association for Cancer Research (AIRC) Study Group; Pfeffer U, Tanda ET, Rozzo C, Paliogiannis P, Cossu A, Ghiorzo P, Palmieri G; Italian Melanoma Intergroup (IMI). Vanni I, et al. Diagn Pathol. 2020 Dec 14;15(1):143. doi: 10.1186/s13000-020-01052-5. Diagn Pathol. 2020. PMID: 33317587 Free PMC article.