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A critical role for IRF5 in regulating allergic airway inflammation.
Byrne AJ, Weiss M, Mathie SA, Walker SA, Eames HL, Saliba D, Lloyd CM, Udalova IA. Byrne AJ, et al. Mucosal Immunol. 2017 May;10(3):716-726. doi: 10.1038/mi.2016.92. Epub 2016 Oct 19. Mucosal Immunol. 2017. PMID: 27759022 Free PMC article.
Anti-TNF Therapy.
Udalova I, Monaco C, Nanchahal J, Feldmann M. Udalova I, et al. Microbiol Spectr. 2016 Aug;4(4). doi: 10.1128/microbiolspec.MCHD-0022-2015. Microbiol Spectr. 2016. PMID: 27726761 Free article. Review.
IRF5 controls both acute and chronic inflammation.
Weiss M, Byrne AJ, Blazek K, Saliba DG, Pease JE, Perocheau D, Feldmann M, Udalova IA. Weiss M, et al. Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11001-6. doi: 10.1073/pnas.1506254112. Epub 2015 Aug 17. Proc Natl Acad Sci U S A. 2015. PMID: 26283380 Free PMC article.