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Lipid Nanocarrier-Based mRNA Therapy: Challenges and Promise for Clinical Transformation.
Li W, Wang C, Zhang Y, Lu Y. Li W, et al. Small. 2024 Jan 29:e2310531. doi: 10.1002/smll.202310531. Online ahead of print. Small. 2024. PMID: 38287729 Review.
Therefore, the effects of the composition of lipid nanocarriers on their key properties are briefly reviewed. In addition, the progress of smart drug delivery by changing the composition of lipid nanocarriers is summarized, and the importance of component design and struct …
Therefore, the effects of the composition of lipid nanocarriers on their key properties are briefly reviewed. In addition, the progre …
Novel Vectors and Administrations for mRNA Delivery.
Bai C, Wang C, Lu Y. Bai C, et al. Small. 2023 Nov;19(46):e2303713. doi: 10.1002/smll.202303713. Epub 2023 Jul 20. Small. 2023. PMID: 37475520 Review.
However, mRNA is challenging to pass through the cell membrane due to its significant negative charges and degradation from RNase, so the key to mRNA therapy is efficient packaging and delivery of it with appropriate vectors. ...
However, mRNA is challenging to pass through the cell membrane due to its significant negative charges and degradation from RNase, so the …
18 results