VacA promotes CagA accumulation in gastric epithelial cells during Helicobacter pylori infection.
Abdullah M, Greenfield LK, Bronte-Tinkew D, Capurro MI, Rizzuti D, Jones NL.
Abdullah M, et al.
Sci Rep. 2019 Jan 10;9(1):38. doi: 10.1038/s41598-018-37095-4.
Sci Rep. 2019.
PMID: 30631092
Free PMC article.
Helicobacter pylori (H. pylori) is the causative agent of gastric cancer, making it the only bacterium to be recognized as a Class I carcinogen by the World Health Organization. The virulence factor cytotoxin associated gene A (CagA) is a known oncoprotein that contributes …
Helicobacter pylori (H. pylori) is the causative agent of gastric cancer, making it the only bacterium to be recognized as a Class I carcino …