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Gadolinium labelled nanoliposomes as the platform for MRI theranostics: in vitro safety study in liver cells and macrophages.
Šimečková P, Hubatka F, Kotouček J, Turánek Knötigová P, Mašek J, Slavík J, Kováč O, Neča J, Kulich P, Hrebík D, Stráská J, Pěnčíková K, Procházková J, Diviš P, Macaulay S, Mikulík R, Raška M, Machala M, Turánek J. Šimečková P, et al. Sci Rep. 2020 Mar 16;10(1):4780. doi: 10.1038/s41598-020-60284-z. Sci Rep. 2020. PMID: 32179785 Free PMC article.
Aryl hydrocarbon receptor-mediated disruption of contact inhibition is associated with connexin43 downregulation and inhibition of gap junctional intercellular communication.
Andrysík Z, Procházková J, Kabátková M, Umannová L, Simečková P, Kohoutek J, Kozubík A, Machala M, Vondráček J. Andrysík Z, et al. Among authors: simeckova p. Arch Toxicol. 2013 Mar;87(3):491-503. doi: 10.1007/s00204-012-0963-7. Epub 2012 Oct 20. Arch Toxicol. 2013. PMID: 23085979
Aryl hydrocarbon receptor negatively regulates expression of the plakoglobin gene (jup).
Procházková J, Kabátková M, Šmerdová L, Pacherník J, Sykorová D, Kohoutek J, Šimečková P, Hrubá E, Kozubík A, Machala M, Vondráček J. Procházková J, et al. Among authors: simeckova p. Toxicol Sci. 2013 Aug;134(2):258-70. doi: 10.1093/toxsci/kft110. Epub 2013 May 20. Toxicol Sci. 2013. PMID: 23690540
Application of Advanced Microscopic Methods to Study the Interaction of Carboxylated Fluorescent Nanodiamonds with Membrane Structures in THP-1 Cells: Activation of Inflammasome NLRP3 as the Result of Lysosome Destabilization.
Knötigová PT, Mašek J, Hubatka F, Kotouček J, Kulich P, Šimečková P, Bartheldyová E, Machala M, Švadláková T, Krejsek J, Vaškovicová N, Skoupý R, Krzyžánek V, Macaulay S, Katzuba M, Fekete L, Ashcheulov P, Raška M, Kratochvílová I, Turánek J. Knötigová PT, et al. Among authors: simeckova p. Mol Pharm. 2019 Aug 5;16(8):3441-3451. doi: 10.1021/acs.molpharmaceut.9b00225. Epub 2019 Jun 24. Mol Pharm. 2019. PMID: 31184896
Proinflammatory Effect of Carbon-Based Nanomaterials: In Vitro Study on Stimulation of Inflammasome NLRP3 via Destabilisation of Lysosomes.
Svadlakova T, Hubatka F, Turanek Knotigova P, Kulich P, Masek J, Kotoucek J, Macak J, Motola M, Kalbac M, Kolackova M, Vankova R, Vicherkova P, Malkova A, Simeckova P, Volkov Y, Prina-Mello A, Kratochvilova I, Fiala Z, Raska M, Krejsek J, Turanek J. Svadlakova T, et al. Among authors: simeckova p. Nanomaterials (Basel). 2020 Feb 27;10(3):418. doi: 10.3390/nano10030418. Nanomaterials (Basel). 2020. PMID: 32120988 Free PMC article.
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