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Multiple copies of the oxytetracycline gene cluster in selected Streptomyces rimosus strains can provide significantly increased titers.
Pikl Š, Carrillo Rincón AF, Slemc L, Goranovič D, Avbelj M, Gjuračić K, Sucipto H, Stare K, Baebler Š, Šala M, Guo M, Luzhetskyy A, Petković H, Magdevska V. Pikl Š, et al. Among authors: sala m. Microb Cell Fact. 2021 Feb 17;20(1):47. doi: 10.1186/s12934-021-01522-5. Microb Cell Fact. 2021. PMID: 33596911 Free PMC article.
Identification of the chelocardin biosynthetic gene cluster from Amycolatopsis sulphurea: a platform for producing novel tetracycline antibiotics.
Lukežič T, Lešnik U, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Raspor P, Herron PR, Hunter IS, Petković H. Lukežič T, et al. Among authors: sala m. Microbiology (Reading). 2013 Dec;159(Pt 12):2524-2532. doi: 10.1099/mic.0.070995-0. Epub 2013 Sep 16. Microbiology (Reading). 2013. PMID: 24043447 Free article.
Construction of a new class of tetracycline lead structures with potent antibacterial activity through biosynthetic engineering.
Lešnik U, Lukežič T, Podgoršek A, Horvat J, Polak T, Šala M, Jenko B, Harmrolfs K, Ocampo-Sosa A, Martínez-Martínez L, Herron PR, Fujs Š, Kosec G, Hunter IS, Müller R, Petković H. Lešnik U, et al. Among authors: sala m. Angew Chem Int Ed Engl. 2015 Mar 23;54(13):3937-40. doi: 10.1002/anie.201411028. Epub 2015 Feb 4. Angew Chem Int Ed Engl. 2015. PMID: 25650563 Free article.
Reference-Grade Genome and Large Linear Plasmid of Streptomyces rimosus: Pushing the Limits of Nanopore Sequencing.
Slemc L, Jakše J, Filisetti A, Baranasic D, Rodríguez-García A, Del Carratore F, Marino SM, Zucko J, Starcevic A, Šala M, Pérez-Bonilla M, Sánchez-Hidalgo M, González I, Reyes F, Genilloud O, Springthorpe V, Goranovič D, Kosec G, Thomas GH, Lucrezia D, Petković H, Tome M. Slemc L, et al. Among authors: sala m. Microbiol Spectr. 2022 Apr 27;10(2):e0243421. doi: 10.1128/spectrum.02434-21. Epub 2022 Apr 4. Microbiol Spectr. 2022. PMID: 35377231 Free PMC article.
1,316 results