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Re-emerging Aspartic Protease Targets: Examining Cryptococcus neoformans Major Aspartyl Peptidase 1 as a Target for Antifungal Drug Discovery.
Kryštůfek R, Šácha P, Starková J, Brynda J, Hradilek M, Tloušt'ová E, Grzymska J, Rut W, Boucher MJ, Drąg M, Majer P, Hájek M, Řezáčová P, Madhani HD, Craik CS, Konvalinka J. Kryštůfek R, et al. Among authors: sacha p. J Med Chem. 2021 May 27;64(10):6706-6719. doi: 10.1021/acs.jmedchem.0c02177. Epub 2021 May 18. J Med Chem. 2021. PMID: 34006103 Free PMC article.
Structure-activity relationship and biochemical evaluation of novel fibroblast activation protein and prolyl endopeptidase inhibitors with α-ketoamide warheads.
Šimková A, Ormsby T, Sidej N, Slavětínská LP, Brynda J, Beranová J, Šácha P, Majer P, Konvalinka J. Šimková A, et al. Among authors: sacha p. Eur J Med Chem. 2021 Nov 15;224:113717. doi: 10.1016/j.ejmech.2021.113717. Epub 2021 Jul 31. Eur J Med Chem. 2021. PMID: 34371463 Free article.
103 results