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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.
Clin Epigenetics. 2019 Jan 7;11(1):4. doi: 10.1186/s13148-018-0601-1.
Clin Epigenetics. 2019.
PMID: 30616689
Free PMC article.
Technologies to study spatial genome organization: beyond 3C.
Übelmesser N, Papantonis A.
Übelmesser N, et al.
Brief Funct Genomics. 2019 Nov 19;18(6):395-401. doi: 10.1093/bfgp/elz019.
Brief Funct Genomics. 2019.
PMID: 31609405
Review.
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HMGB1 coordinates SASP-related chromatin folding and RNA homeostasis on the path to senescence.
Sofiadis K, Josipovic N, Nikolic M, Kargapolova Y, Übelmesser N, Varamogianni-Mamatsi V, Zirkel A, Papadionysiou I, Loughran G, Keane J, Michel A, Gusmao EG, Becker C, Altmüller J, Georgomanolis T, Mizi A, Papantonis A.
Sofiadis K, et al. Among authors: ubelmesser n.
Mol Syst Biol. 2021 Jun;17(6):e9760. doi: 10.15252/msb.20209760.
Mol Syst Biol. 2021.
PMID: 34166567
Free PMC article.
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RNA polymerase II is required for spatial chromatin reorganization following exit from mitosis.
Zhang S, Übelmesser N, Josipovic N, Forte G, Slotman JA, Chiang M, Gothe HJ, Gusmao EG, Becker C, Altmüller J, Houtsmuller AB, Roukos V, Wendt KS, Marenduzzo D, Papantonis A.
Zhang S, et al. Among authors: ubelmesser n.
Sci Adv. 2021 Oct 22;7(43):eabg8205. doi: 10.1126/sciadv.abg8205. Epub 2021 Oct 22.
Sci Adv. 2021.
PMID: 34678064
Free PMC article.
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Enhancer-promoter contact formation requires RNAPII and antagonizes loop extrusion.
Zhang S, Übelmesser N, Barbieri M, Papantonis A.
Zhang S, et al. Among authors: ubelmesser n.
Nat Genet. 2023 May;55(5):832-840. doi: 10.1038/s41588-023-01364-4. Epub 2023 Apr 3.
Nat Genet. 2023.
PMID: 37012454
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