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Paradoxical activation of oncogenic signaling as a cancer treatment strategy.
Cancer Discov. 2024 Mar 27. doi: 10.1158/2159-8290.CD-23-0216. Online ahead of print.
Cancer Discov. 2024.
PMID: 38533987
IκB kinase-α coordinates BRD4 and JAK/STAT signaling to subvert DNA damage-based anticancer therapy.
Pecharromán I, Solé L, Álvarez-Villanueva D, Lobo-Jarne T, Alonso-Marañón J, Bertran J, Guillén Y, Montoto Á, Martínez-Iniesta M, García-Hernández V, Giménez G, Salazar R, Santos C, Garrido M, Borràs E, Sabidó E, Bonfill-Teixidor E, Iurlaro R, Seoane J, Villanueva A, Iglesias M, Bigas A, Espinosa L.
Pecharromán I, et al. Among authors: alvarez villanueva d.
EMBO J. 2023 Nov 2;42(21):e114719. doi: 10.15252/embj.2023114719. Epub 2023 Sep 22.
EMBO J. 2023.
PMID: 37737566
Free article.
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p53 wild-type colorectal cancer cells that express a fetal gene signature are associated with metastasis and poor prognosis.
Solé L, Lobo-Jarne T, Álvarez-Villanueva D, Alonso-Marañón J, Guillén Y, Guix M, Sangrador I, Rozalén C, Vert A, Barbachano A, Lop J, Salido M, Bellosillo B, García-Romero R, Garrido M, González J, Martínez-Iniesta M, López-Arribillaga E, Salazar R, Montagut C, Torres F, Iglesias M, Celià-Terrassa T, Muñoz A, Villanueva A, Bigas A, Espinosa L.
Solé L, et al. Among authors: alvarez villanueva d.
Nat Commun. 2022 May 23;13(1):2866. doi: 10.1038/s41467-022-30382-9.
Nat Commun. 2022.
PMID: 35606354
Free PMC article.
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Dynamic chromatin association of IκBα is regulated by acetylation and cleavage of histone H4.
Marruecos L, Bertran J, Álvarez-Villanueva D, Mulero MC, Guillén Y, Palma LG, Floor M, Vert A, Arce-Gallego S, Pecharroman I, Batlle L, Villà-Freixa J, Ghosh G, Bigas A, Espinosa L.
Marruecos L, et al. Among authors: alvarez villanueva d.
EMBO Rep. 2021 Aug 4;22(8):e52649. doi: 10.15252/embr.202152649. Epub 2021 Jul 5.
EMBO Rep. 2021.
PMID: 34224210
Free PMC article.
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