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Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19.
Szabo R, Petrișor C, Bodolea C, Dobre V, Tranca S, Clichici S, Szabo I, Melinte RM, Mocan T. Szabo R, et al. Pharmaceutics. 2023 Feb 14;15(2):646. doi: 10.3390/pharmaceutics15020646. Pharmaceutics. 2023. PMID: 36839968 Free PMC article.
Blocking the interleukin 6-hepcidin pathway with Tocilizumab could present favorable outcomes. The aim of this study was to evaluate if Tocilizumab influences survival, the occurrence of sepsis, anemia and transfusions in critically ill patients suffering from COVID-19. Th …
Blocking the interleukin 6-hepcidin pathway with Tocilizumab could present favorable outcomes. The aim of this study was to evaluate …
Hyperferritinemia, Low Circulating Iron and Elevated Hepcidin May Negatively Impact Outcome in COVID-19 Patients: A Pilot Study.
Szabo R, Petrisor C, Bodolea C, Simon R, Maries I, Tranca S, Mocan T. Szabo R, et al. Antioxidants (Basel). 2022 Jul 14;11(7):1364. doi: 10.3390/antiox11071364. Antioxidants (Basel). 2022. PMID: 35883855 Free PMC article.
Hepcidin and interleukin 6, along with routine blood parameters, were determined and outcomes, such as death, multiple organ damage (MOD), anemia, and need for transfusions, were assessed. The results of this pilot study indicate that iron metabolism parameters individuall …
Hepcidin and interleukin 6, along with routine blood parameters, were determined and outcomes, such as death, multiple organ damage (MOD), a …