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High-yield production of (R)-acetoin in Saccharomyces cerevisiae by deleting genes for NAD(P)H-dependent ketone reductases producing meso-2,3-butanediol and 2,3-dimethylglycerate.
Metab Eng. 2021 Jul;66:68-78. doi: 10.1016/j.ymben.2021.04.001. Epub 2021 Apr 20.
Metab Eng. 2021.
PMID: 33845171
Efficient production of acetoin in Saccharomyces cerevisiae by disruption of 2,3-butanediol dehydrogenase and expression of NADH oxidase.
Bae SJ, Kim S, Hahn JS.
Bae SJ, et al.
Sci Rep. 2016 Jun 9;6:27667. doi: 10.1038/srep27667.
Sci Rep. 2016.
PMID: 27279026
Free PMC article.
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Improvement of d-Lactic Acid Production in Saccharomyces cerevisiae Under Acidic Conditions by Evolutionary and Rational Metabolic Engineering.
Baek SH, Kwon EY, Bae SJ, Cho BR, Kim SY, Hahn JS.
Baek SH, et al. Among authors: bae sj.
Biotechnol J. 2017 Oct;12(10). doi: 10.1002/biot.201700015. Epub 2017 Aug 9.
Biotechnol J. 2017.
PMID: 28731533
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Promoters inducible by aromatic amino acids and γ-aminobutyrate (GABA) for metabolic engineering applications in Saccharomyces cerevisiae.
Kim S, Lee K, Bae SJ, Hahn JS.
Kim S, et al. Among authors: bae sj.
Appl Microbiol Biotechnol. 2015 Mar;99(6):2705-14. doi: 10.1007/s00253-014-6303-5. Epub 2015 Jan 10.
Appl Microbiol Biotechnol. 2015.
PMID: 25573467
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Multiplex Gene Disruption by Targeted Base Editing of Yarrowia lipolytica Genome Using Cytidine Deaminase Combined with the CRISPR/Cas9 System.
Bae SJ, Park BG, Kim BG, Hahn JS.
Bae SJ, et al.
Biotechnol J. 2020 Jan;15(1):e1900238. doi: 10.1002/biot.201900238. Epub 2019 Nov 11.
Biotechnol J. 2020.
PMID: 31657874
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Redirection of pyruvate flux toward desired metabolic pathways through substrate channeling between pyruvate kinase and pyruvate-converting enzymes in Saccharomyces cerevisiae.
Kim S, Bae SJ, Hahn JS.
Kim S, et al. Among authors: bae sj.
Sci Rep. 2016 Apr 7;6:24145. doi: 10.1038/srep24145.
Sci Rep. 2016.
PMID: 27052099
Free PMC article.
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