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2010 | 1 |
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A new class of dual-targeted antivirals: monophosphorylated acyclovir prodrug derivatives suppress both human immunodeficiency virus type 1 and herpes simplex virus type 2.
J Infect Dis. 2010 Feb 15;201(4):635-43. doi: 10.1086/650343.
J Infect Dis. 2010.
PMID: 20085496
Free PMC article.
Acyclovir is activated into a HIV-1 reverse transcriptase inhibitor in herpesvirus-infected human tissues.
Lisco A, Vanpouille C, Tchesnokov EP, Grivel JC, Biancotto A, Brichacek B, Elliott J, Fromentin E, Shattock R, Anton P, Gorelick R, Balzarini J, McGuigan C, Derudas M, Götte M, Schinazi RF, Margolis L.
Lisco A, et al.
Cell Host Microbe. 2008 Sep 11;4(3):260-270. doi: 10.1016/j.chom.2008.07.008.
Cell Host Microbe. 2008.
PMID: 18779052
Free PMC article.
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