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Rotaviruses associate with cellular lipid droplet components to replicate in viroplasms, and compounds disrupting or blocking lipid droplets inhibit viroplasm formation and viral replication.
J Virol. 2010 Jul;84(13):6782-98. doi: 10.1128/JVI.01757-09. Epub 2010 Mar 24.
J Virol. 2010.
PMID: 20335253
Free PMC article.
Physicochemical analysis of rotavirus segment 11 supports a 'modified panhandle' structure and not the predicted alternative tRNA-like structure (TRLS).
Biswas S, Li W, Manktelow E, Lever J, Easton LE, Lukavsky PJ, Desselberger U, Lever AM.
Biswas S, et al.
Arch Virol. 2014 Feb;159(2):235-48. doi: 10.1007/s00705-013-1802-8. Epub 2013 Aug 13.
Arch Virol. 2014.
PMID: 23942952
Free PMC article.
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