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Table representation of search results timeline featuring number of search results per year.
Year | Number of Results |
---|---|
2020 | 1 |
2021 | 2 |
2022 | 2 |
2024 | 1 |
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6 results
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Page 1
Therapeutics in the Pipeline Targeting α-Synuclein for Parkinson's Disease.
Pharmacol Rev. 2022 Jan;74(1):207-237. doi: 10.1124/pharmrev.120.000133.
Pharmacol Rev. 2022.
PMID: 35017177
Free PMC article.
Review.
Decreasing the intrinsically disordered protein α-synuclein levels by targeting its structured mRNA with a ribonuclease-targeting chimera.
Tong Y, Zhang P, Yang X, Liu X, Zhang J, Grudniewska M, Jung I, Abegg D, Liu J, Childs-Disney JL, Gibaut QMR, Haniff HS, Adibekian A, Mouradian MM, Disney MD.
Tong Y, et al.
Proc Natl Acad Sci U S A. 2024 Jan 9;121(2):e2306682120. doi: 10.1073/pnas.2306682120. Epub 2024 Jan 5.
Proc Natl Acad Sci U S A. 2024.
PMID: 38181056
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Tumor suppressor PALB2 maintains redox and mitochondrial homeostasis in the brain and cooperates with ATG7/autophagy to suppress neurodegeneration.
Huo Y, Sawant A, Tan Y, Mahdi AH, Li T, Ma H, Bhatt V, Yan R, Coleman J, Dreyfus CF, Guo JY, Mouradian MM, White E, Xia B.
Huo Y, et al.
PLoS Genet. 2022 Apr 11;18(4):e1010138. doi: 10.1371/journal.pgen.1010138. eCollection 2022 Apr.
PLoS Genet. 2022.
PMID: 35404932
Free PMC article.
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MicroRNA-7 Protects Against Neurodegeneration Induced by α-Synuclein Preformed Fibrils in the Mouse Brain.
Zhang J, Zhao M, Yan R, Liu J, Maddila S, Junn E, Mouradian MM.
Zhang J, et al.
Neurotherapeutics. 2021 Oct;18(4):2529-2540. doi: 10.1007/s13311-021-01130-6. Epub 2021 Oct 25.
Neurotherapeutics. 2021.
PMID: 34697773
Free PMC article.
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Striatal ΔFosB gene suppression inhibits the development of abnormal involuntary movements induced by L-Dopa in rats.
Beck G, Zhang J, Fong K, Mochizuki H, Mouradian MM, Papa SM.
Beck G, et al.
Gene Ther. 2021 Dec;28(12):760-770. doi: 10.1038/s41434-021-00249-7. Epub 2021 Mar 11.
Gene Ther. 2021.
PMID: 33707771
Free PMC article.
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Translation of the intrinsically disordered protein α-synuclein is inhibited by a small molecule targeting its structured mRNA.
Zhang P, Park HJ, Zhang J, Junn E, Andrews RJ, Velagapudi SP, Abegg D, Vishnu K, Costales MG, Childs-Disney JL, Adibekian A, Moss WN, Mouradian MM, Disney MD.
Zhang P, et al.
Proc Natl Acad Sci U S A. 2020 Jan 21;117(3):1457-1467. doi: 10.1073/pnas.1905057117. Epub 2020 Jan 3.
Proc Natl Acad Sci U S A. 2020.
PMID: 31900363
Free PMC article.
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