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The GPCR-Gαs-PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure.
Wu VH, Yung BS, Faraji F, Saddawi-Konefka R, Wang Z, Wenzel AT, Song MJ, Pagadala MS, Clubb LM, Chiou J, Sinha S, Matic M, Raimondi F, Hoang TS, Berdeaux R, Vignali DAA, Iglesias-Bartolome R, Carter H, Ruppin E, Mesirov JP, Gutkind JS. Wu VH, et al. Nat Immunol. 2023 Aug;24(8):1318-1330. doi: 10.1038/s41590-023-01529-7. Epub 2023 Jun 12. Nat Immunol. 2023. PMID: 37308665 Free PMC article.
Mitochondrial Homeostasis in Acute Organ Failure.
Stallons LJ, Funk JA, Schnellmann RG. Stallons LJ, et al. Curr Pathobiol Rep. 2013 Sep;1(3):10.1007/s40139-013-0023-x. doi: 10.1007/s40139-013-0023-x. Curr Pathobiol Rep. 2013. PMID: 24386614 Free PMC article.
Hyperglycemia in the absence of cilia accelerates cystogenesis and induces renal damage.
Sas KM, Yin H, Fitzgibbon WR, Baicu CF, Zile MR, Steele SL, Amria M, Saigusa T, Funk J, Bunni MA, Siegal GP, Siroky BJ, Bissler JJ, Bell PD. Sas KM, et al. Am J Physiol Renal Physiol. 2015 Jul 1;309(1):F79-87. doi: 10.1152/ajprenal.00652.2014. Epub 2015 Apr 22. Am J Physiol Renal Physiol. 2015. PMID: 25904703 Free PMC article.