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Theratyping of the Rare CFTR Genotype A559T in Rectal Organoids and Nasal Cells Reveals a Relevant Response to Elexacaftor (VX-445) and Tezacaftor (VX-661) Combination.
Int J Mol Sci. 2023 Jun 19;24(12):10358. doi: 10.3390/ijms241210358.
Int J Mol Sci. 2023.
PMID: 37373505
Free PMC article.
CFTR Modulators Rescue the Activity of CFTR in Colonoids Expressing the Complex Allele p.[R74W;V201M;D1270N]/dele22_24.
Kleinfelder K, Somenza E, Farinazzo A, Conti J, Lotti V, Latorre RV, Rodella L, Massella A, Tomba F, Bertini M, Sorio C, Melotti P.
Kleinfelder K, et al.
Int J Mol Sci. 2023 Mar 8;24(6):5199. doi: 10.3390/ijms24065199.
Int J Mol Sci. 2023.
PMID: 36982273
Free PMC article.
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