Raquel Ortega - Search Results

Year	Number of Results
2009	3
2010	3
2011	3
2013	1
2014	2
2015	4
2016	3
2017	3
2018	5
2019	1
2021	3
2022	3
2023	3
2024	3

1

The APE2 nuclease is essential for DNA double-strand break repair by microhomology-mediated end joining.

Fleury H, MacEachern MK, Stiefel CM, Anand R, Sempeck C, Nebenfuehr B, Maurer-Alcalá K, Ball K, Proctor B 3rd, Belan O, Taylor E, Ortega R, Dodd B, Weatherly L, Dansoko D, Leung JW, Boulton SJ, Arnoult N. Fleury H, et al. Among authors: ortega r. Mol Cell. 2023 May 4;83(9):1429-1445.e8. doi: 10.1016/j.molcel.2023.03.017. Epub 2023 Apr 11. Mol Cell. 2023. PMID: 37044098 Free PMC article.

2

Antibiotic Resistance and Virulence Profiles of Klebsiella pneumoniae Strains Isolated From Different Clinical Sources.

Ballén V, Gabasa Y, Ratia C, Ortega R, Tejero M, Soto S. Ballén V, et al. Among authors: ortega r. Front Cell Infect Microbiol. 2021 Sep 1;11:738223. doi: 10.3389/fcimb.2021.738223. eCollection 2021. Front Cell Infect Microbiol. 2021. PMID: 34540722 Free PMC article.

3

Combinatory EHMT and PARP inhibition induces an interferon response and a CD8 T cell-dependent tumor regression in PARP inhibitor-resistant models.

Nguyen LL, Watson ZL, Ortega R, Woodruff ER, Jordan KR, Iwanaga R, Yamamoto TM, Bailey CA, Jeong AD, Guntupalli SR, Behbakht K, Gbaja V, Arnoult N, Chuong EB, Bitler BG. Nguyen LL, et al. Among authors: ortega r. bioRxiv [Preprint]. 2023 Feb 23:2023.02.23.529773. doi: 10.1101/2023.02.23.529773. bioRxiv. 2023. PMID: 36865165 Free PMC article. Preprint.

4

Evolution of the Inhibitory and Non-Inhibitory ε, ζ, and IF₁ Subunits of the F₁F_O-ATPase as Related to the Endosymbiotic Origin of Mitochondria.

Mendoza-Hoffmann F, Zarco-Zavala M, Ortega R, Celis-Sandoval H, Torres-Larios A, García-Trejo JJ. Mendoza-Hoffmann F, et al. Among authors: ortega r. Microorganisms. 2022 Jul 7;10(7):1372. doi: 10.3390/microorganisms10071372. Microorganisms. 2022. PMID: 35889091 Free PMC article. Review.

5

Putative Repurposing of Lamivudine, a Nucleoside/Nucleotide Analogue and Antiretroviral to Improve the Outcome of Cancer and COVID-19 Patients.

García-Trejo JJ, Ortega R, Zarco-Zavala M. García-Trejo JJ, et al. Among authors: ortega r. Front Oncol. 2021 Jul 21;11:664794. doi: 10.3389/fonc.2021.664794. eCollection 2021. Front Oncol. 2021. PMID: 34367956 Free PMC article. Review.

6

Control of rotation of the F₁F_O-ATP synthase nanomotor by an inhibitory α-helix from unfolded ε or intrinsically disordered ζ and IF₁ proteins.

Mendoza-Hoffmann F, Zarco-Zavala M, Ortega R, García-Trejo JJ. Mendoza-Hoffmann F, et al. Among authors: ortega r. J Bioenerg Biomembr. 2018 Oct;50(5):403-424. doi: 10.1007/s10863-018-9773-9. Epub 2018 Sep 28. J Bioenerg Biomembr. 2018. PMID: 30267331 Review.

7

Design, Synthesis, and Biological Evaluation of 5-Formyl-pyrrolo[3,2-b]pyridine-3-carboxamides as New Selective, Potent, and Reversible-Covalent FGFR4 Inhibitors.

Yang F, Chen X, Song X, Ortega R, Lin X, Deng W, Guo J, Tu Z, Patterson AV, Smaill JB, Chen Y, Lu X. Yang F, et al. Among authors: ortega r. J Med Chem. 2022 Nov 10;65(21):14809-14831. doi: 10.1021/acs.jmedchem.2c01319. Epub 2022 Oct 24. J Med Chem. 2022. PMID: 36278929

8

Rationally designed peptide nanosponges for cell-based cancer therapy.

Wang H, Yapa AS, Kariyawasam NL, Shrestha TB, Kalubowilage M, Wendel SO, Yu J, Pyle M, Basel MT, Malalasekera AP, Toledo Y, Ortega R, Thapa PS, Huang H, Sun SX, Smith PE, Troyer DL, Bossmann SH. Wang H, et al. Among authors: ortega r. Nanomedicine. 2017 Nov;13(8):2555-2564. doi: 10.1016/j.nano.2017.07.004. Epub 2017 Jul 25. Nanomedicine. 2017. PMID: 28754467

9

Design, Synthesis, and Biological Evaluation of Aminoindazole Derivatives as Highly Selective Covalent Inhibitors of Wild-Type and Gatekeeper Mutant FGFR4.

Shao M, Chen X, Yang F, Song X, Zhou Y, Lin Q, Fu Y, Ortega R, Lin X, Tu Z, Patterson AV, Smaill JB, Chen Y, Lu X. Shao M, et al. Among authors: ortega r. J Med Chem. 2022 Mar 24;65(6):5113-5133. doi: 10.1021/acs.jmedchem.2c00096. Epub 2022 Mar 10. J Med Chem. 2022. PMID: 35271262

10

Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors.

Deng W, Chen X, Jiang K, Song X, Huang M, Tu ZC, Zhang Z, Lin X, Ortega R, Patterson AV, Smaill JB, Ding K, Chen S, Chen Y, Lu X. Deng W, et al. Among authors: ortega r. ACS Med Chem Lett. 2021 Mar 22;12(4):647-652. doi: 10.1021/acsmedchemlett.1c00052. eCollection 2021 Apr 8. ACS Med Chem Lett. 2021. PMID: 33859803 Free PMC article.

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