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Metabolic responses to xenin-25 are altered in humans with Roux-en-Y gastric bypass surgery.
Peptides. 2016 Aug;82:76-84. doi: 10.1016/j.peptides.2016.06.001. Epub 2016 Jun 7.
Peptides. 2016.
PMID: 27288245
Free PMC article.
Clinical Trial.
Hormonal Responses to Cholinergic Input Are Different in Humans with and without Type 2 Diabetes Mellitus.
Chowdhury S, Wang S, Dunai J, Kilpatrick R, Oestricker LZ, Wallendorf MJ, Patterson BW, Reeds DN, Wice BM.
Chowdhury S, et al.
PLoS One. 2016 Jun 15;11(6):e0156852. doi: 10.1371/journal.pone.0156852. eCollection 2016.
PLoS One. 2016.
PMID: 27304975
Free PMC article.
Clinical Trial.
Item in Clipboard
Xenin-25 potentiates glucose-dependent insulinotropic polypeptide action via a novel cholinergic relay mechanism.
Wice BM, Wang S, Crimmins DL, Diggs-Andrews KA, Althage MC, Ford EL, Tran H, Ohlendorf M, Griest TA, Wang Q, Fisher SJ, Ladenson JH, Polonsky KS.
Wice BM, et al.
J Biol Chem. 2010 Jun 25;285(26):19842-53. doi: 10.1074/jbc.M110.129304. Epub 2010 Apr 26.
J Biol Chem. 2010.
PMID: 20421298
Free PMC article.
Item in Clipboard
Global biochemical profiling identifies β-hydroxypyruvate as a potential mediator of type 2 diabetes in mice and humans.
Zhang S, Wang S, Puhl MD, Jiang X, Hyrc KL, Laciny E, Wallendorf MJ, Pappan KL, Coyle JT, Wice BM.
Zhang S, et al.
Diabetes. 2015 Apr;64(4):1383-94. doi: 10.2337/db14-1188. Epub 2014 Nov 3.
Diabetes. 2015.
PMID: 25368100
Free PMC article.
Item in Clipboard
Xenin-25 amplifies GIP-mediated insulin secretion in humans with normal and impaired glucose tolerance but not type 2 diabetes.
Wice BM, Reeds DN, Tran HD, Crimmins DL, Patterson BW, Dunai J, Wallendorf MJ, Ladenson JH, Villareal DT, Polonsky KS.
Wice BM, et al.
Diabetes. 2012 Jul;61(7):1793-800. doi: 10.2337/db11-1451. Epub 2012 Apr 20.
Diabetes. 2012.
PMID: 22522617
Free PMC article.
Clinical Trial.
Item in Clipboard
The combination of GIP plus xenin-25 indirectly increases pancreatic polypeptide release in humans with and without type 2 diabetes mellitus.
Chowdhury S, Wang S, Patterson BW, Reeds DN, Wice BM.
Chowdhury S, et al.
Regul Pept. 2013 Nov 10;187:42-50. doi: 10.1016/j.regpep.2013.10.003. Epub 2013 Oct 29.
Regul Pept. 2013.
PMID: 24183983
Free PMC article.
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